<a href="/content/musical-creativity-brain-structure-and-education">5086</a>
Musical Creativity, Brain Structure, and Education
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/musical-creativity-brain-structure-and-education"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon19_0.jpg?itok=scZxiKlS" width="100" height="49" alt="Musical Creativity, Brain Structure, and Education" /></a></div></div></div>
David Bashwiner
David
Bashwiner
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study examining the transfer effects of music on brain anatomy and physiology among New Mexican older adolescents and adults who have shown sustained interest and success in STEM fields. The study will perform advanced statistical modeling on data from a battery of psychological tests and brain imaging studies. It will determine links between individuals' past musical experience and differences in brain structure and function.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of New Mexico Main Campus</div></div></div>
<a href="/content/ucla-arts-impact-measurement-system">1226</a>
The UCLA Arts Impact Measurement System
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/ucla-arts-impact-measurement-system"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon1.jpg?itok=HD4k9eCh" width="100" height="49" alt="The UCLA Arts Impact Measurement System" /></a></div></div></div>
Robert Bilder, PhD
Robert
Bilder
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The Research Lab at UCLA will develop a reliable, valid, flexible, and scalable Arts Impact Measurement System (AIMS), an assessment tool for integration with mobile devices. Using psychometrics, AIMS will measure self-reported health and well-being outcomes associated with arts participation. The assessment tool will be pilot-tested in partnership with Herbie Hancock Institute of Jazz (in public-school outreach programs) and on campus arts-engagement experiences to promote well-being among students, staff, and faculty—in partnership with the Semel Mindful Music program. The researchers intend to make the tool freely available to the international arts community, and will facilitate public release of the data, after safeguarding for confidentiality and privacy protections. This project lays the groundwork for greater translational research focused on understanding the fundamental cognitive and biological mechanisms by which the arts affect well-being.</p>
<p>The research agenda aims to address the following research questions:</p>
<ul>
<li>What are the social, emotional, physical, and/or physiological health benefits of participating in the arts for individuals, groups, or societies?</li>
<li>What physiological or psychological mechanisms or group dynamics are at work in achieving those benefits or related outcomes?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of California, Los Angeles</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><img alt="UCLA logo" height="39" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/ucla.png" width="83" /></p>
<p> </p>
</div></div></div>
<a href="/content/effectiveness-%C2%A0clinically-designed-improvisatory-music-anxiety-individuals-mild-moderate">10926</a>
Effectiveness of Clinically Designed Improvisatory Music on Anxiety in Individuals with Mild to Moderate Alzheimer’s Disease
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/effectiveness-%C2%A0clinically-designed-improvisatory-music-anxiety-individuals-mild-moderate"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon28_2.jpg?itok=TuI-BAEc" width="100" height="49" alt="" /></a></div></div></div>
Borna Bonakdarpour
Borna
Bonakdarpour
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a mixed-methods study that will examine the effectiveness of a clinically designed improvisational music program on anxiety among older adults with mild to moderate Alzheimer's disease. Additional Project Description: Under a single group, multi-phased design, all participants will serve as a control group for the study and will engage in a "no-intervention" period, followed by the intervention itself. During the music intervention sessions, participants will attend virtual and in-person improvisational music experiences. Multiple assessments will be collected before and after the no-intervention period and the intervention period, to test for changes for a period of time. Researchers will collect information on anxiety and worry, and, through physiological assessments, data on heart rate, blood pressure, respiratory rate, and brain images. Intended Beneficiaries: This project has the potential to benefit older adults with anxiety and mild to moderate Alzheimer's disease, their caretakers, and other working partners and community collaborators such as healthcare providers, music therapists, and music organizations. Intended Outcome: Research, statistics, and general information about the arts benefit the arts sector and other fields.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Northwestern University</div></div></div>
<a href="/content/arts-research-chronic-stress-lab-arcs">1231</a>
Arts Research on Chronic Stress Lab (ARCS)
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/arts-research-chronic-stress-lab-arcs"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon12.jpg?itok=-PYaJ8BE" width="100" height="49" alt="Arts Research on Chronic Stress Lab (ARCS)" /></a></div></div></div>
Joke Bradt, PhD, MT-BC
Joke
Bradt, Girija Kaimal
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Drexel University will develop a NEA Research Lab titled <strong>Arts Research on Chronic Stress Lab (ARCS)</strong> to explore the intersection of the arts, health, and social/emotional well-being. Research studies in the ARCS lab will focus on therapeutic art-making, creative arts therapies and connect with community-based arts organizations to enhance social engagement and overall well-being in individuals who have been affected by chronic stressors including chronic illness, prolonged caregiving, academic stressors and trauma, as well as testing the effects of creative arts therapies in pediatric cancer care settings, for post-surgical pain management and opioid usage, and for military service members who have post-traumatic stress and/or traumatic brain injury. The studies use interdisciplinary mixed methods experimental designs, incorporate a range of data sources (biomarkers, standardized surveys, narratives, artwork and music) and examine short term and long-term health outcomes. The Drexel team will collaborate and consult with arts practitioners from a range of sites in the Philadelphia and Washington DC region as well as sites affiliated with the Arts Endowment's Creative Forces: NEA Military Healing Arts Network.</p>
<p>The research agenda aims to address the following research questions:</p>
<ul>
<li>What are the social and/or emotional-related health benefits of participating in the arts for individuals, groups, or societies?</li>
<li>What physiological or psychological mechanisms or group dynamics are at work in achieving those benefits or related outcomes?</li>
<li>How do these benefits or related outcomes vary by one's socioeconomic characteristics, demographics and behavioral patterns, and one's stage of life?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Drexel University</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Girija Kaimal, EdD, ATR-BC</li>
</ul>
</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this Lab, see their <a href="http://drexel.edu/cnhp/research/faculty/KaimalGirija/arcs_lab/">Research Lab webpage</a>.</p>
<p><img alt="Drexel University logo" height="116" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/drexel.png" width="113" /></p>
</div></div></div>
<a href="/content/research-equity-arts-childhood-reach">4906</a>
Research on Equity via the Arts in Childhood (REACH)
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/research-equity-arts-childhood-reach"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon27_0.jpg?itok=u7hPxBZf" width="100" height="49" alt="Research on Equity via the Arts in Childhood (REACH)" /></a></div></div></div>
Eleanor Brown, PhD
Eleanor
Brown
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The cooperative agreement will involve the design and implementation of a research agenda to address the following questions: a) Do high-quality musical experiences improve young children's capacity for self-regulation?; b) Are music-related improvements in self-regulation mediated or explained by changes in children's neurophysiological function?; c) What specific aspects of high-quality musical experiences, defined in terms of caregiver/educator behaviors and pedagogical strategies, promote these changes in neurophysiological function and/or capacity for self-regulation?; and d) What are the distinct versus common effects of music (either alone or combined with movement) and other arts and non-arts interventions, and at what levels of participation? </p>
<p>West Chester University of Pennsylvania, in partnership with research firm WolfBrown, will establish the Research on Equity via the Arts in Childhood (REACH) Lab to advance scientific understanding of how arts experiences may foster positive self-regulation outcomes (both physiological and self-reported outcomes) as well as promote equity for young children facing the effects of poverty, racism, and related forms of adversity. Researchers will examine outcomes of arts participation as related to three different contexts: 1) interactions with caregivers in toddlerhood, 2) pre-school classrooms, and 3) out-of-school instruction following school entry. Research methods to address these questions include correlational, quasi-experimental, and experimental designs featuring a blend of observational systems, laboratory assessments, and neurophysiological measures. </p>
<p>The REACH Lab will develop a website, post quarterly blog posts, host a biennial convening, produce research reports, create applied tools with accompanying toolkits, as well as train undergraduate students in rigorous methods for studying the health benefits of arts engagement from a behavioral neuroscience approach. Partnering arts organizations include Settlement Music School, Carnegie Hall, and Play on Philly. Research findings will guide refinement of these partnering organizations' program offerings.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">West Chester University</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Steven Holochwost, PhD</li>
<li>Dennie Palmer Wolf</li>
</ul>
</div></div></div>
<a href="/content/impact-piano-training-cognitive-performance-and-psychosocial-wellbeing-older-adults">8496</a>
The Impact of Piano Training on Cognitive Performance and Psychosocial Wellbeing in Older Adults
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/impact-piano-training-cognitive-performance-and-psychosocial-wellbeing-older-adults"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon10_0.jpg?itok=f9eKscoE" width="100" height="49" alt="" /></a></div></div></div>
Jennifer Bugos
Jennifer
Bugos
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study of the impact of piano training on cognitive, psychosocial, and neurophysiological dimensions of well-being in older adults. In partnership with the Hillsborough County Department of Aging Services, researchers will employ a randomized, controlled trial study design, comparing such outcome variables as verbal fluency, working memory, mood, and self-efficacy in older adults who receive piano training versus older adults who receive either computer-based auditory training or no treatment at all. Brain wave measurements will allow researchers to track allocations of attentional and working memory, while biomarkers will be used to gauge stress levels and immune function during the study period.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of South Florida</div></div></div>
<a href="/content/study-examining-how-technology-based-musical-training-program-prepares-early-learners">8501</a>
A Study Examining How a Technology-Based Musical Training Program Prepares Early Learners
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/study-examining-how-technology-based-musical-training-program-prepares-early-learners"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon9.jpg?itok=fM9eQgjC" width="100" height="49" alt="" /></a></div></div></div>
Jennifer Bugos
Jennifer
Bugos
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study examining how a technology-based musical training program prepares early learners. This project will experimentally evaluate the effects of a preschool program focused on developing creativity, gross motor skills (drums using a computer tablet), and vocal skills. Researchers will study whether participation in the program is related to student outcomes such as working memory, executive functioning, inhibition, and auditory processing in at-risk young children. Participants will be recruited from local preschools and Head Start centers and will be randomly assigned to one of three groups: a music group, a building blocks group, and a no-treatment group. Researchers will use pre- and post-assessments to test whether children in the music group significantly improve in outcomes compared with the other groups.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of South Florida</div></div></div>
<a href="/content/cognition-and-coordination%C2%A0across-lifespan-music-calm">10306</a>
Cognition and Coordination Across the Lifespan in Music (CALM)
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/cognition-and-coordination%C2%A0across-lifespan-music-calm"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon13_1.jpg?itok=bJxHphck" width="100" height="49" alt="" /></a></div></div></div>
Jennifer Bugos
Jennifer
Bugos
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The project will include the design and implementation of a research agenda to addres the following questions: a) What are the effects of music training interventions on music achievement, bimanual coordination, exeuctive functions (a set of mental skills that include working memory, flexible thinking nad self-control)_ and attention across the lifespan; b) What are the most effective neurocognitive transfer and technologies to measure those outcomes?; c) BHow much training is necessary to generate sustainable benefits?; d) How do learning-related outcomes vary by age,SES, other demographc/behavioral patterns, and by health/disability status; and e) What are the benefits and rleated outcomes for specific music. approaches to arts learning in formal or informal settings? The keystone study will examine the effects of fine motor learning (piano instruction), gross motor learning (percussion instruction) and no motor learning (music appreciation) in a randomized sample of children, young adults and older adults. The study will use standardized measures of music achievement, executive functioning, attention and motor skills assesesd prior to participation, as well as at follow up intervals of 1, 2, and 3 months. </p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of South Florida</div></div></div>
<a href="/content/improving-neurological-functioning-autistic-children-through-music">5101</a>
Improving Neurological Functioning in Autistic Children through Music
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/improving-neurological-functioning-autistic-children-through-music"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon20_0.jpg?itok=TgWsUs30" width="100" height="49" alt="Improving Neurological Functioning in Autistic Children through Music" /></a></div></div></div>
John Carpente
John
Carpente
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study examining whether an improvisational music therapy program can improve outcomes for children with autism. In partnership with the University of Tennessee Health Science Center, researchers will test whether participation in the 12-week music program can improve neurological functioning of children with Autism Spectrum Disorder (ASD) and, furthermore, whether there is a relationship between children's engagement ability and activity within the mirror neuron system of children with ASD. The study will include a comparison group of neurotypical children. Assessments will include behavioral observations of engagement, affect, and interaction; surveys of parents and assessments of family quality of life; and brain imaging measurement using electroencephalography (EEG).</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Molloy College</div></div></div>
<a href="/content/songmaking-group-sing-music-hallucinations-and-predictive-coding">3686</a>
Songmaking in a group (SING): Music; Hallucinations and Predictive Coding
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/songmaking-group-sing-music-hallucinations-and-predictive-coding"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon3.jpg?itok=999pdD34" width="100" height="49" alt="Songmaking in a group (SING): Music; Hallucinations and Predictive Coding" /></a></div></div></div>
Philip Corlett, PhD
Philip
Corlett
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>People with psychotic illnesses perceive and believe things about themselves, the outside world and other people that do not obtain. This can be very distressing for them, their family members and friends. Listening to and performing music can help mitigate this distress, but we do not know why. This project aims to find out. Perceiving and believing, about self and others, is achieved by making predictions and updating those predictions in light of new evidence, particularly if that new evidence is very reliable or precise. One way that music might help psychosis involves this precision. By making one set of predictions more precise—predictions about music— other predictions can change. This might be why we tap our toes or sing along to music we enjoy. We propose that experiencing more reliable predictions about ones’ actions (by singing) and other people (by singing along with them) will help to change the predictions that underwrite the symptoms of psychosis. We will test whether this is true in an initial R61 study, tracking the change in performance of a series of prediction-based tasks as a result of musical experience by prosecuting three specific aims: Specific Aim 1 will examine the impact of song- making in a group (SING) on conditioned hallucination task performance, a procedure that safely and reliably engenders hallucinations in the laboratory. We predict SING will reduce the number and mechanisms of hallucinations in the laboratory. Specific Aim 2 will examine how social learning changes with SING. Using a reputation learning task, we will measure social learning rates. We predict they will increase with SING. Specific Aim 3 will examine participants’ subjective experience of self-hood and how they change with SING using computational linguistic analysis. We predict SING will decrease linguistic markers of distress. If those studies prove successful, we will – in a follow-up R33 study – use metrics from the R61 to decompose the musical intervention into its key ingredients – asking whether it is important to be active (or merely passively experience music), and whether owning the music produced is important to its impact on precision of processing. These studies will help us refine whether, how and to whom we deliver musical intervention for serious mental illness.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R61</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Yale University</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10015353&icde=52558048&ddparam=&ddvalue=&ddsub=&cr=4&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/impact-culturally-based-live-music-intervention-metabolites-and-metabolic-pathways">11151</a>
The impact of a culturally-based live music intervention on the metabolites and metabolic pathways associated with chronic stress and the risk of preterm birth in Black women
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/impact-culturally-based-live-music-intervention-metabolites-and-metabolic-pathways"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon25_5.jpg?itok=Q83CpdXm" width="100" height="49" alt="" /></a></div></div></div>
Elizabeth Corwin, Joanne Loewy
Elizabeth
Corwin, Joanne Loewy
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The health disparity in preterm birth (PTB) that exists in the United States (US) is a national crisis. Pregnant Black women have a 50% higher risk of PTB compared to pregnant White women in the US, and their infants are more than twice as likely to die. This disparity continues despite decades of research and tried intervention. Over ten years ago, the National Academy of Medicine identified Black women’s exposure to chronic stress as among the most important risk factors contributing to this health disparity and called for additional research as necessary. Although additional research has been conducted, the high rates of PTB among Black women have continued unabated. Thus, to address this significant critical need, we have brought together an exemplary team of researchers and clinicians with unique and complementary expertise. With this team, we will conduct a first of its kind clinic trial: testing the efficacy of a 10-week, live, culturally congruent music intervention compared to a similarly delivered 10-week sham control, to reduce the biological impact of chronic stress at the most fundamental level -- the molecules and metabolic pathways that are affected by stress. We further propose implementing the Music Characterization System (MCS) to identify the musical mechanisms underlying any benefit. Black women in the US often are exposed to chronic stress related to their race, sex, socioeconomic status, and social determinants of health including neighborhood and household food insecurity. Our study stems from our team’s previous research demonstrating that within a similar population of pregnant Black women, chronic stress was associated with changes in maternal metabolites and metabolic pathways linked to oxidative stress, energy production, and myelination, all potentially influencing pregnancy and newborn outcomes. This study also stems from our team’s rigorous research showing the power of live music to reduce stress and improve outcomes. Based on the National Institute of Minority Health and Health Disparities Research Framework, we will recruit 142 pregnant Black women during their 1st trimester of pregnancy and implement the Music Intervention or sham control beginning in the 2nd trimester. Women will collect saliva samples for later metabolomic analysis and complete surveys at the 1st, 5th, and 10th-week verbal or sham session. Birth outcomes will be determined from careful review of the labor and delivery record. Music is one of the earliest, most traditional art forms in human history, while metabolomics is one of the newest and most advanced technologies available in the world today. By combining the very old with the very new in this innovative study, we have the opportunity to identify a means by which the beneficial effects of live, culturally relevant music chosen by a pregnant woman and implemented therapeutically, can reduce the biological impact of the daily stressors to which she is exposed, and as a result, reduce one of the most persistent health disparities of our time, PTB.</p>
<p>For more information on this project, see their <a href="https://reporter.nih.gov/project-details/10559006">NIH Research Portfolio</a>.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R01</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Columbia University</div></div></div>
<a href="/content/chorus-impact-study-singing-lifetime-1">8476</a>
The Chorus Impact Study: Singing for a Lifetime
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/chorus-impact-study-singing-lifetime-1"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon25_2.jpg?itok=JOBS4152" width="100" height="49" alt="" /></a></div></div></div>
Catherine Dehoney
Catherine
Dehoney
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study examining the impact of choral singing on older adults. The study will assess the types and frequency of choral singing among older adults, its perceived importance to social connectedness and physical health, and improvements to cognitive function. In partnership with the National Center for Creative Aging, researchers will administer focus group interviews and online surveys to the general public, choir members, older adults, and family caregivers. Where possible, trend comparisons will be made with 2003 and 2009 survey findings.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Chorus America Association</div></div></div>
<a href="/content/effects%C2%A0-music-quality-life-across-lifespan-meta-analysis">8481</a>
Effects of Music on Quality of Life across the Lifespan: A Meta Analysis
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/effects%C2%A0-music-quality-life-across-lifespan-meta-analysis"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon23_0.jpg?itok=PLPfdngv" width="100" height="49" alt="" /></a></div></div></div>
Cheryl Dileo
Cheryl
Dileo
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a meta-analysis of research literature on music's non-clinical or non-therapeutic effects on Americans' quality of life. The analysis will focus on music's effects on the following outcome areas: physiological; psychological; social; behavioral; and cognitive.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Temple University</div></div></div>
<a href="/content/project-unmute-feasibility-acceptability-and-potential-effects-intergenerational-music">10301</a>
Project Unmute: The feasibility, acceptability, and potential effects of an intergenerational music program delivered by adolescents to older adults with declining cognition
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/project-unmute-feasibility-acceptability-and-potential-effects-intergenerational-music"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon15_3.jpg?itok=vuXLRUw8" width="100" height="49" alt="" /></a></div></div></div>
Jennifer Dorris
Jennifer
Dorris
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a mixed-methods study of an intergenerational music program delievered by adolescent musicaisn to older adults with early-stage cognitive decline</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Pittsburgh</div></div></div>
<a href="/content/sing-your-saunter-using-self-generated-rhythmic-cues-enhance-gait-parkinsons">3691</a>
Sing for Your Saunter: Using Self-Generated Rhythmic Cues to Enhance Gait in Parkinson's
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/sing-your-saunter-using-self-generated-rhythmic-cues-enhance-gait-parkinsons"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon4.jpg?itok=7_g8ftYT" width="100" height="49" alt="Sing for Your Saunter: Using Self-Generated Rhythmic Cues to Enhance Gait in Parkinson's" /></a></div></div></div>
Gammon M Earhart, PT, PhD, FAPTA
Gammon
Earhart
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Older adults, and particularly those with Parkinson disease (PD), may experience walking difficulties that negatively impact their daily function and quality of life. This project will examine the impact of music and singing on walking performance, with the goal of understanding what types of rhythmic cues are most helpful to people with Parkinson disease and older adults. Our pilot work suggests that imagined, mental singing while walking helps people walk faster with greater stability, whereas walking to music also helps people walk faster but with reduced stability. In Aim 1, we will compare walking while mentally singing to walking while listening to music, using personalized cues tailored to each person's walking performance. We will also test whether finger tapping, a rhythmic task similar to walking in many ways, responds similarly while mentally singing and listening to music. In Aim 2, we will investigate the brain mechanisms underlying the enhancements in movement performance seen with mental singing or music listening. We will use magnetic resonance imaging (MRI) to measure brain activity during finger tapping with and without various cues to understand which areas of the brain are more or less responsive to different types of cues. Using the information gained in the first two aims, we will then conduct an intervention study in Aim 3 to compare and contrast the effects of music-based vs. singing-based training for people with PD. We will determine which training method results in the greatest improvements in walking and tapping performance and measure changes in brain activity with training. We will also ask the participants how acceptable and usable the different training approaches are. This work is among the first to focus on singing as an intervention to improve walking in PD and is innovative in its use of this novel, untapped, highly accessible, adaptable, low-cost approach that has the potential to enhance walking, thereby improving everyday function and quality of life for people with PD.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R61</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Washington University</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10016174&icde=52558065&ddparam=&ddvalue=&ddsub=&cr=2&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/effect-music-and-suggestion-chronic-pain-aging-adults-randomized-controlled-study">4961</a>
Effect of Music and Suggestion for Chronic Pain in Aging Adults: A Randomized Controlled Study
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/effect-music-and-suggestion-chronic-pain-aging-adults-randomized-controlled-study"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon2.jpg?itok=MSbqK12g" width="100" height="49" alt="Effect of Music and Suggestion for Chronic Pain in Aging Adults: A Randomized Controlled Study" /></a></div></div></div>
Gary Elkins
Gary
Elkins
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a randomized controlled study examining the effect of music on pain management in older adults. The clinical trial will compare outcomes across older adults in one of three groups: one receiving music alone; another receiving music with guided instructions; and a third (non-arts) group receiving structured attention and standard care. Outcome variables of interest include chronic pain management and sleep. The findings will inform public knowledge about how interventions using music—with or without guided instructions—may offer a non-phamacological treatment option for older adults experiencing pain, by posing minimal risk and burden to patients.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Baylor University</div></div></div>
<a href="/content/project-chroma">3601</a>
Project Chroma
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/project-chroma"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon5.jpg?itok=WElbOOOF" width="100" height="49" alt="Project Chroma" /></a></div></div></div>
Christopher Fagundes, PhD
Christopher
Fagundes
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>In partnership with Musiqa, Rice University will establish a research hub for measuring the effects of music-making and music engagement on cognitive and social-emotional well-being. The Lab's keystone study—a randomized, waitlist-control trial—will examine older adults with mild cognitive impairment who will undergo a six-week course combining musical exposure, creativity, and performance. The program culminates in creation of a final composition, with participants performing to family, caregivers, and members of the community. Outcome measures will include pre- and post-intervention assessments on intelligence and cognitive flexibility; loneliness, social support, and perceived psychological stress; and neural markers such as brain modularity and flexibility. The researchers hypothesize that the program studied under the Research Lab can provide a model for addressing the need for low-cost, nonpharmacological interventions for cognitive impaired patients and their caregivers.</p>
<p>The research agenda will address the following research aims:</p>
<ul>
<li>To study the cognitive and mental health outcomes experienced by cognitively impaired subjects receiving a music-based intervention;</li>
<li>To study the physiological (brain-based) mechanism of action for a music-based intervention in improving or slowing the decline of cognitively impaired patients; and</li>
<li>To conduct a survey of how music interventions benefits the social and emotional well-being of caregivers and affects their ability to look after their cognitively impaired charges.</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Rice University</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Anthony Brandt, PhD</li>
<li>Bryan Denny, PhD</li>
</ul>
</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this Lab, see their <a href="http://arches.rice.edu/">Research Lab webpage</a>.</p>
<p><img alt="Rice University logo" height="66" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/rice.png" width="169" /></p>
</div></div></div>
<a href="/content/relation-between-bimanual-coordination-and-interhemispheric-communication-musicians">5071</a>
The Relation Between Bimanual Coordination and Interhemispheric Communication in Musicians
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/relation-between-bimanual-coordination-and-interhemispheric-communication-musicians"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon28_1.jpg?itok=fXYaYNRT" width="100" height="49" alt="The Relation Between Bimanual Coordination and Interhemispheric Communication in Musicians" /></a></div></div></div>
Beth Fisher
Beth
Fisher
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study comparing hand coordination and inter-brain communication skills in musicians. The study will comprise three distinct groups: non-musicians; musicians with symmetrical hand use (e.g., piano-players); and musicians with asymmetrical hand use (e.g., string-players). Researchers will conduct several task assessments among these groups to understand the relationship between bimanual coordination and inter-hemispheric inhibition-a cortical mechanism underlying most forms of motor control. The study asks whether the functional inter-hemispheric interactions and bimanual motor coordination acquired by musicians who have trained intensively with a musical instrument can generalize to other bimanual skills.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Southern California</div></div></div>
<a href="/content/randomized-controlled-trial-utilizing-arts-improve-health-resilience-and-well-being">4976</a>
A Randomized Controlled Trial Utilizing the Arts to Improve Health, Resilience, and Well-Being in Individuals with Chronic Health Conditions in Underserved Neighborhoods
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/randomized-controlled-trial-utilizing-arts-improve-health-resilience-and-well-being"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon1_0.jpg?itok=LvWPeaj4" width="100" height="49" alt="A Randomized Controlled Trial Utilizing the Arts to Improve Health, Resilience, and Well-Being in Individuals with Chronic Health Conditions in Underserved Neighborhoods" /></a></div></div></div>
Lisa Gallagher
Lisa
Gallagher
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a randomized controlled trial examining the arts' ability to improve health, resilience, and well-being in individuals with chronic health conditions. Researchers at Cleveland Clinic's Arts Medicine Institute will implement an eight-week program involving music, art, art appreciation, theater, movement, and writing; primary data will be collected with pre-, post-, and follow-up assessments of leisure activity participation, mental well-being, global health, resilient coping, and depression. Study participants, who must have at least one diagnosed chronic health condition, will be recruited from underserved neighborhoods in Cleveland or Akron, Ohio. The researchers also will conduct interviews to gather qualitative information on participants' experiences with the program, and on its impact and meaning in their lives.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Cleveland Clinic</div></div></div>
<a href="/content/impact-learning-music-based-strategies-caregiver-stress-levels-and-caregiverinfant-social">4991</a>
The Impact of Learning Music-Based Strategies on Caregiver Stress Levels and Caregiver/Infant Social-Emotional Competence: Demonstrating Feasibility Among At-Risk Families in Rural Appalachia
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/impact-learning-music-based-strategies-caregiver-stress-levels-and-caregiverinfant-social"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon23.jpg?itok=RakiyUUb" width="100" height="49" alt="The Impact of Learning Music-Based Strategies on Caregiver Stress Levels and Caregiver/Infant Social-Emotional Competence: Demonstrating Feasibility Among At-Risk Families in Rural Appalachia" /></a></div></div></div>
Kamile Geist
Kamile
Geist
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a feasibility study examining the impact of music-based learning activities on at-risk caregivers and their infants in rural Appalachia. Researchers will work with the healthcare facility Help Me Grow, serving caregivers of infants who have been identified as at-risk due to trauma, exposure to substance abuse, and economic disadvantage. Project activities include: developing and implementing an eight-week music-based online curriculum for at-home healthcare providers to teach caregivers; measuring the curriculum's impact; and providing community arts-based support for the program participants. Effects of the program will be assessed via the stress hormone cortisol and through surveys on caregiver stress and children's social-emotional behaviors.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Ohio University Main Campus</div></div></div>
<a href="/content/mason-arts-research-center">3606</a>
Mason Arts Research Center
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/mason-arts-research-center"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon6.jpg?itok=EomR8iDC" width="100" height="49" alt="Creativity icon on purple background" /></a></div></div></div>
Thalia Goldstein, Adam Winsler, Kim Sheridan
Thalia
Goldstein, Adam Winsler, Kim Sheridan
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The George Mason University Arts Research Center (“MasonARC”) is a multidisciplinary research center involving the expertise of three faculty members at George Mason University, with a research focus on arts engagement, child development, and education. Studies will examine the outcomes of arts education in low-income, ethnically diverse high school students; the effect of theatre training on social skills; and students’ sense of agency. Additionally, the research center will involve public engagement and distribution of research through a <a href="https://masonarc.gmu.edu/">website</a> and a regularly updated blog on arts research across domains, and a biennial conference on the latest research and practice in arts and child development. The MasonARC includes strong arts partnerships with two of Virginia’s most established arts education and producing nonprofits (<a href="http://va-rep.org/">Virginia Repertory Theatre</a> and the <a href="https://masonacademy.gmu.edu/">Mason Community Arts Academy</a>).</p>
<p>The research agenda will address the following research questions:</p>
<ul>
<li>What are the social and/or emotional-related health benefits of participating in the arts?;</li>
<li>What psychological mechanisms or group dynamics are at work in achieving those benefits or related outcomes?;</li>
<li>What kinds of art forms are invoked in these relationships, and at what levels of participation?; and</li>
<li>How do these benefits or related outcomes vary by age, socioeconomic characteristics, other demographics and behavioral patterns, and/or disability status?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">George Mason University</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Adam Winsler, PhD</li>
<li>Kimberly Sheridan, EdD</li>
</ul>
</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this Lab, see their <a href="https://masonarc.gmu.edu/">Research Lab webpage</a>.</p>
<p><img alt="George Mason University logo" height="129" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/GeorgeMason.png" width="201" /></p>
</div></div></div>
<a href="/content/longitudinal-positive-effects-marching-band-participation-university-students-different">8516</a>
The Longitudinal Positive Effects Of Marching Band Participation On University Students From Different Racial/Ethnic Backgrounds
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/longitudinal-positive-effects-marching-band-participation-university-students-different"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon12_1.jpg?itok=KdxkIvwV" width="100" height="49" alt="" /></a></div></div></div>
Thalia Goldstein, Dasean Young
Thalia
Goldstein, Dasean Young
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study examining the longitudinal effects of marching band participation on university students from different racial/ethnic backgrounds. The study will assess student outcomes across three types of institutions: a Historically Black College and University (HBCU); a university with a racially/ethnically diverse student body; and a university with predominantly white students. Three times throughout the school year, participating students will complete measures on self-efficacy, stress, belongingness, and attitudes about diversity. Researchers also will use social network analyses to examine development of cross-race friendships arising from marching arts participation (marching band, drum line, and color guard).</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">George Mason University</div></div></div>
<a href="/content/music-appreciation-after-cochlear-implantation">1246</a>
Music Appreciation after Cochlear Implantation
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/music-appreciation-after-cochlear-implantation"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon7.jpg?itok=XLDGPYz-" width="100" height="49" alt="People playing music and music notes icon" /></a></div></div></div>
Raymond Goldsworthy, PhD
Raymond
Goldsworthy
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Cochlear implants are medical devices that restore a remarkable degree of hearing to people who would otherwise be profoundly deaf. These devices generally restore enough hearing that recipients can understand spoken speech even in noisy environments. However, most recipients express dissatisfaction with music. This proposal centers on understanding the challenges that implant users face and the strategies that they adopt as they learn to appreciate music with this new way of hearing. The proposed research is organized into three aims: Aim 1: Characterize music appreciation after cochlear implantation. The proposed research balances qualitative and quantitative methods to examine the emergence of music appreciation after cochlear implantation. Qualitative methods will include semi-structured interviews and focus groups designed to clarify the obstacles that implant users face as they learn to appreciate music with their new sense of hearing. Quantitative methods include surveys of music appreciation and quality of life, and auditory assessments of music and speech perception. The primary hypothesis is that music appreciation is predictive of key domains of quality of life including positive affect and well-being, and satisfaction with social roles and activities. Aim 2: Determine if pitch training improves cochlear implant speech comprehension. The proposed research tests for a causal relationship between pitch salience and key features of speech perception including talker discrimination, prosody detection, and speech recognition in competing speech. Cochlear implant users and their normal-hearing peers will take part in a crossover study to determine if pitch training improves aspects of music and speech perception compared to a visual task used as a control. The primary hypothesis is that pitch training will improve speech comprehension for cochlear implant users, but not for their normal-hearing peers. Aim 3: Test the limits of pitch coding in cochlear implants. The proposed research bypasses conventional sound processing to study the salience of pitch provided by electrode location and stimulation rate. These two stimulation cues are the primary cues for providing a sense of pitch to cochlear implant users. Our work has shown that implant users are able to learn to use this information to hear pitch with better resolution far better than previously thought. The primary hypothesis is that cochlear implant users have a latent ability to hear pitch associated with stimulation rate, but that they require experience to learn how to hear this new information. In each aim, we compliment psychophysical methods with an innovative approach combining EEG and near- infrared spectroscopy. The results will establish the importance of music training for improving cochlear implant outcomes, both in terms of hearing abilities and quality of life. The results will lead to changes in how music is encoded into implant stimulation, providing better outcomes for recipients. More generally, this project will shape understanding of neural coding of music and its role in social adjustment following traumatic experiences.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R01</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Southern California</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10017675&icde=52557517&ddparam=&ddvalue=&ddsub=&cr=2&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/music-training-bilingualism-and-executive-functioning">3656</a>
Music Training; Bilingualism and Executive Functioning
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/music-training-bilingualism-and-executive-functioning"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon8.jpg?itok=jEHPl2Sa" width="100" height="49" alt="Music Training; Bilingualism and Executive Functioning" /></a></div></div></div>
Assal Habibi, PhD
Assal
Habibi
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The proposed study aims to investigate the effects of music training on the development of executive function skills (EF) in a population of school-age children, from under-resourced communities of Los Angeles. Executive function (EF) refers to a number of core cognitive capacities that allows the coordination of thoughts, decision making and planning. Development of these skills is increasingly recognized as an important contributor to well-being throughout the life span. There is particular interest in EF skills in children, given the considerable brain and cognitive developments associated with this period of life. Furthermore, low socio-economic status on its own may affect negatively the course of EF development. On the other hand, children from these disadvantaged communities have been shown to benefit the most from any intervention that has the potential to improve EF. Playing music is a task that engages many different brain regions; it requires the concurrent recruitment of distinct sensory and motor systems and their interplay with the attention and affective systems. Learning to play a musical instrument requires mastering abilities related to EF such as auditory working memory, motor inhibition and cognitive flexibility and has been suggested to benefit EF. Two groups will be recruited to participate in the proposed study: the experimental group will be monolingual, native English- speaking children, ages 9-11, from under-resourced communities of South and Central Los Angeles, who have had 2 years of music training with YOLA, a community-based free music education program. The comparison group will consist of children of the same age, from the same neighborhoods and socio-economic background, also monolingual, who did not have any previous experience of music training. Electrophysiological (EEG), neuroimaging (MRI) and behavioral probes will be used to assess the impact of music training on EF and its neural underpinnings. The findings from this study will provide answers to the ongoing discussion about music’s role in childhood education curricula, especially in underprivileged communities for whom access to private or out of school music education is limited, or none. By focusing on these communities, our findings will address a gap in the knowledge of child development and may serve to guide more effective public policies. In addition, under separate funding, we are evaluating the effects of music training, also with YOLA, in a bilingual child population from the same socio-economic background, using the same approach. We will compare the results from the two studies. Like music training, bilingualism has also been shown to have positive influence on EF development. However, it is not clear whether these two learning experiences influence EF similarly, or through distinct mechanisms. Comparison of the results obtained here in monolingual children with those obtained in the parallel bilingual group will allow the evaluation of the developmental effects of these two learning experiences. It will also allow the understanding of the differences, or similarities, of cognitive and brain development in children living in under-resourced urban communities.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R21</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Southern California</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10016842&icde=52557888&ddparam=&ddvalue=&ddsub=&cr=1&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/neurodevelopmental-investigation-how-music-education-can-benefit-executive-function-and">4986</a>
A Neurodevelopmental Investigation of How Music Education Can Benefit Executive Function and Emotion Regulation in Adolescents
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/neurodevelopmental-investigation-how-music-education-can-benefit-executive-function-and"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon28_0.jpg?itok=Kgw6LWY2" width="100" height="49" alt="A Neurodevelopmental Investigation of How Music Education Can Benefit Executive Function and Emotion Regulation in Adolescents" /></a></div></div></div>
Assal Habibi
Assal
Habibi
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a neurodevelopmental investigation of how music education can benefit executive function and emotion regulation in adolescents. This quasi-experimental study will examine the development of executive function in teenagers from underprivileged communities in Los Angeles. Teens who have had five years of music training through an El Sistema-inspired community music program will be compared with two matched-comparison groups: one comprising teens who participated in a community-based sports program for five years, but who have not taken any systematic musical training; and another comprising teens who have not had any systematic after-school music or sports training. All participants will be recruited from an existing longitudinal study for which comprehensive brain, cognitive, and social-emotional data were collected before the students received training, and for four consecutive years afterward. The study will assess the long-term benefits of music training to development from childhood to early adolescence. Neuroimaging (MRI/fMRI) and behavioral measures will be used to assess development of brain structure and function.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Southern California</div></div></div>
<a href="/content/effects-music-training-neurodevelopment-and-associated-health-outcomes">12306</a>
Effects of Music Training on Neurodevelopment and Associated Health Outcomes
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/effects-music-training-neurodevelopment-and-associated-health-outcomes"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon28_3.jpg?itok=gQJ7cdUE" width="100" height="49" alt="" /></a></div></div></div>
Assal Habibi, PhD
Assal
Habibi
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>While there is a growing body of evidence suggesting that music training benefits brain development, the evidence is not conclusive and rigorously designed randomized control trial (RCT) neuroimaging studies are needed to provide a definitive answer to whether and which brain circuits are enhanced by music training and how. We aim to address this gap: we propose an RCT to robustly test the hypothesis that systematic music training will benefit development of brain inhibition control circuitry among Hispanic youth from underserved communities. Prior work including ours provided suggestive evidence that long-term music training in children may lead to neuroplastic functional changes in the associated frontal brain circuitry and improvement of inhibitory control. During the R61 phase, we will test the feasibility (recruitment, retention, adherence and intent to continue) of a RCT on 40 Hispanic children between ages 6-8, of whom will be assigned to a 24-month intervention trial targeting community and group-focused after school music training (MG) or to an after-school program comprising arts, book clubs, ethnic and culture studies without specific focus on systematic music training, the control group (CG). We will use multi-modal imaging and behavioral probes to measure two aspects of inhibition control: (1) response inhibition by using a stop-signal task and (2) delayed gratification using a computerized task wherein children will be asked to choose immediate vs. delayed monetary rewards. Neuroimaging measures will be obtained twice, pre and post 2-yr intervention. Behavioral measures will be obtained at baseline and yearly thereafter. During the R33 phase, we will additionally recruit 74 Hispanic children between ages 6-8 and assess them with the same imaging and behavioral measurements using the same testing timeline as in R61. This is the first RCT using neuroimaging to assess whether and how music training enhances brain inhibition control circuitry. By focusing on Hispanic children from underserved communities our results will shed light on the effects of music training on development of brain function. And early life brain-to-behavior changes induced by music training may have long-term positive effects on an individual's health and success.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R61/R33</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Southern California</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Shan Luo</p>
</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://reporter.nih.gov/project-details/10694807">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/music-based-interventions-enhance-interpersonal-synchrony-caregiver-care-recipient">12411</a>
Music-Based Interventions to Enhance Interpersonal Synchrony for the Caregiver-Care Recipient Relationship in Alzheimer’s Disease and Related Dementias
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/music-based-interventions-enhance-interpersonal-synchrony-caregiver-care-recipient"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon13_2.jpg?itok=vDs_XTpU" width="100" height="49" alt="" /></a></div></div></div>
Assal Habibi
Assal
Habibi
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>USC's Brain and Music Lab will partner with the university's Thornton School of Music and its Alzheimer Disease Research Center to conduct a series of studies examining the effects of music engagement through choir training on hearing, communication, and psychosocial well-being of individuals with or at risk for Alzheimer's disease, and their caregivers. The lab, which corresponds with the NEA research priority topic of "measuring the arts' impacts on health and wellness for individuals," will consider factors such as age, genetic predisposition, socio-economic characteristics, demographic backgrounds, and the caregiver role in relation to the benefits of music engagement on the cognitive and socioemotional well-being of older adults. For the lab's keystone study, a team of interdisciplinary researchers will conduct a randomized-controlled trial of a 16-week music intervention for older adults from diverse backgrounds, with some participants assigned to an experimental group (community choir-singing) and others to a control group (music-listening). Pre- and post-intervention data will be collected from participants through a variety of measurement tools such as electrophysiology, wearable sensors, and psychosocial metrics. Future studies conducted by the lab will identify the effects of choir-singing on emotional stress and quality of life for caregivers of individuals with dementia in particular, and will explore other benefits of co-participation in choir-singing by individuals with dementia and their caregivers. The team will share its findings and resources through a website, academic publications and presentations, and mainstream media outlets; non-technical products will be available in both English and Spanish. The team also hopes to disseminate research and products through the Sound Health Network, a separate NEA initiative in partnership with University of California San Francisco.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Southern California</div></div></div>
<a href="/content/tuning-heartstrings-music-education-persistence-and-parasympathetic-nervous-system">4981</a>
Tuning the Heartstrings: Music Education, Persistence, and the Parasympathetic Nervous System
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/tuning-heartstrings-music-education-persistence-and-parasympathetic-nervous-system"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon29_0.jpg?itok=E0aeq_vv" width="100" height="49" alt="Tuning the Heartstrings: Music Education, Persistence, and the Parasympathetic Nervous System" /></a></div></div></div>
Steven Holochwost
Steven
Holochwost
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a randomized controlled study examining the impact of music education on behavioral and neurophysiological pathways for academic performance. Researchers will study the effects of music education on young children's persistence and their parasympathetic nervous system activity. In partnership with WolfBrown, Play on Philly will conduct a study in a school in a low-income area of Philadelphia, randomly assigning students to either a music education program or to a waitlisted control group. Students in the intervention group will receive music education daily across the school year. Measurement tools include pre- and post-assessments for cardiac activity, executive function (a set of mental skills that include working memory, flexible thinking, and self-control), and persistence. The study will provide insights into whether and how music education exerts a positive effect on academic performance by reorganizing children's behavioral and neurophysiological functioning.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Play On Philly</div></div></div>
<a href="/content/large-scale-nested-studies-impact-music-brain-and-behavioral-development">3636</a>
Large-scale nested studies of the impact of music on brain and behavioral development
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/large-scale-nested-studies-impact-music-brain-and-behavioral-development"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon9_0.jpg?itok=K3UNX-We" width="100" height="49" alt="A child singing and a study icon on green background" /></a></div></div></div>
John Iversen, PhD
John
Iversen
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Does music help a child's development and health? A positive impact of music is supported by a rapidly growing body of scientific work that has shown that musicians' brains are shaped by music in ways that could underlie benefits of musical training not only on musical abilities, but also on fundamental non-musical skills such as attention, executive function, social/emotional functioning, and language, skills that form the foundation for healthy functioning academically and in society. Despite this, deep questions remain: does music participation cause change, or is it a reflection of some underlying, general factor? What is the relative contribution of music activity vs. music ability? To complement past studies (which have typically relied on correlative observations along with some small-scale intervention trials and longitudinal studies) there is now an unprecedented opportunity to leverage large-scale, high-dimensional neurodevelopmental studies by creatively nesting within them questions about the impact of music and development, focusing on active participation in music training. Such an approach is attractive in its power and resource efficiency. This three- year project seeks to address the impact of music training on development using two approaches building on our prior work: 1) Detailed analysis of existing large-scale longitudinal neurobehavioral data from the PLING/SIMPHONY study, and 2) Analysis of initial data and laying of further groundwork to empower the unprecedented ABCD (Adolescent Brain and Cognitive Development) study of over 11,000 youths over 10 years, to comprehensively address the role of music in brain and cognitive development and physical and mental health. Together, these two resources span the school years, collecting thousands of behavioral and brain variables for each individual and timepoint. This proposal will apply new methods in development to build models of the impact of experiences on the development of brain and behavior with an unprecedented detail.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R01</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of California, San Diego</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10017116&icde=52557587&ddparam=&ddvalue=&ddsub=&cr=2&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/early-academic-readiness-and-learning-intervention-earli">1261</a>
Early Academic Readiness and Learning Intervention (EARLI)
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/early-academic-readiness-and-learning-intervention-earli"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon10.jpg?itok=-cEmDDvd" width="100" height="49" alt="Brain image and icon on blue background" /></a></div></div></div>
John Iversen, PhD, Timothy Brown, PhD
John
Iversen, Tim Brown
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The University of California, San Diego will establish a group of Early Academic Readiness and Learning Intervention (EARLI) studies that will test the influence of various school-day musical interventions on early childhood development. Activities include a phased research plan beginning with an initial feasibility study of a vocal music intervention, with a focus on assessing language, brain, and social development outcomes. Children in Transitional Kindergarten (TK) classes who participate in a daily singing program will be assessed three times a year on cognitive, affective, social, academic, and music skills through standardized and experimental performance-based measures, observational measures, and teacher and parent questionnaires. The research agenda will progress toward a major, multidimensional study of the effects of several hypothesized enhancing and protective aspects of musical experiences during childhood. This Research Lab builds on an interdisciplinary team's deep experience in music and large-scale longitudinal child development studies, bridging fields such as cognitive science, developmental psychology, neuroscience, musicology, and education. The ultimate goal is to identify and characterize potential effects and to define their interactions with child's age, status of brain development, and genetic variation. Partners include nonprofit arts partner San Diego Children's Choir and education partner Vista Unified School District.</p>
<p>The research agenda aims to address the following research questions:</p>
<ul>
<li>Can improved outcomes in learning, emotional well-being, and/or school engagement be demonstrated for early childhood music interventions? If so, what is the strength of the relationship, and are these effects sustained through elementary school?;</li>
<li>How do learning-related outcomes associated with arts participation vary by age, socioeconomic characteristics, and other demographic and behavioral patterns?; and</li>
<li>What are the most sensitive neurocognitive tests and technologies to measure outcomes?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of California, San Diego</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Terry Jernigan, PhD</li>
<li>Matthew Doyle, EdD</li>
<li>Margie Orem, MA</li>
</ul>
</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this Lab, see their <a href="http://nearesearchlab.ucsd.edu/">Research Lab webpage</a>.</p>
<p><img alt="UC San Diego logo" height="39" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/ucsd.png" width="206" /></p>
</div></div></div>
<a href="/content/following-sound-music-comparing-effects-music-vs-non-music-based-interentions-auditory-and">8616</a>
Following the Sound of Music-Comparing the Effects of Music vs. Non-Music Based Interentions on Auditory and Cognitive Processing in Older Adults
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/following-sound-music-comparing-effects-music-vs-non-music-based-interentions-auditory-and"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon5_0.jpg?itok=Nf2bATZc" width="100" height="49" alt="" /></a></div></div></div>
Susanne Jaeggi
Susanne
Jaeggi
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The overall objective of the proposed work is to test the benefits of a music-based intervention on speech-in- competition abilities in an older adult population that includes individuals that may be at risk of Alzheimer's disease and related dementias (ADRD). Age-related hearing difficulties are prevalent, with speech-in- competition difficulties being a common challenge amongst older adults. Critically, these difficulties and frustrations often lead to social isolation and decreased cognitive engagement, and they are associated with an increased risk of developing ADRD. There is evidence suggesting that musical training is associated with cognitive advantages in older adults, including preserved ability for speech-in-competition. However, to date, there is extremely limited knowledge and lack of experimental evidence explaining how music might benefit speech-in-competition abilities, along with more basic auditory processes and/or cognitive functions. We aim to contribute to uncovering the underlying mechanisms driving the potential effects of music and attention through an innovative, attention-based music listening intervention that cultivates auditory and attentional skills akin to those developed during formal instrumental training. To disentangle potential effects of music and attention and to get at the underlying mechanisms of music effects, we will compare outcomes of this attention-based music intervention with those of two active control interventions that consist of either passive music listening or active listening to non-music sounds. Specific aims are to develop and test the feasibility of music and control interventions and assessments targeting auditory processing and cognition (R61; Aim 1); test for intervention- specific improvements in speech-in-competition using a randomized-controlled trial (R33; Aim 2); and determine whether experimental and control interventions differentially impact measures of auditory processing, memory, and attention, and test how these may mediate performance on measures of speech-in-competition (R33; Aim 3). Long-term objectives are to understand the key mechanisms underlying the benefits of music with the overall goal to inform interventions aimed at mitigating the effects of ADRD. This proposal is transformative in that it utilizes an innovative approach to uncover potential benefits and underlying mechanisms of music by testing the added benefits of interventions and testing their benefits against a broad set of outcomes measures that can be used to further understand the malleability of auditory processes and cognition in aging. In addition, the intervention is cost-effective, easily administrable, and accessible to individuals who may not possess the physical capabilities or resources that formal instrumental practice demands. In addition, music has been shown to provide other benefits including mood regulation and psychological well-being, and as such, the intervention may have benefits that go beyond the auditory or cognitive domain. Overall, the proposed work aims to contribute to the amelioration and/or prevention of cognitive decline in individuals that may be at risk for developing ADRD.</p>
<p>For more information on this project, see their <a href="https://reporter.nih.gov/search/mH8DWLiJeE28kLLoLUTp2Q/project-details/10273909">NIH Research Portfolio</a>.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R61</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of california, Irvine</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Aaron Seitz</p>
</div></div></div>
<a href="/content/role-involuntary-repetitive-music-imagery-memory-consolidation">3661</a>
The Role of Involuntary Repetitive Music Imagery in Memory Consolidation
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/role-involuntary-repetitive-music-imagery-memory-consolidation"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon11.jpg?itok=aoWnkMNB" width="100" height="49" alt="The Role of Involuntary Repetitive Music Imagery in Memory Consolidation" /></a></div></div></div>
Petr Janata, PhD
Petr
Janata
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Two experiences with music are particularly prevalent: the vivid reliving of memories triggered by music and having fragments of music repeating, often incessantly, in one's mind. The proposed research examines the relationship of these two phenomena, testing the hypothesis that involuntary repetitive musical imagery (IRMI) helps to consolidate memories not only for the music itself, but also for non-musical information that has been associated with the music. Study participants will be exposed to novel repeating 8-second pieces of music (loops) as they tap along with it in a manner that is pleasing to them. Previous work has shown that this results in IRMI for such musical material. One week following this exposure, memory for the loops is tested. Participants are then exposed to loops played in isolation, faces and biographical information presented in isolation, or loops paired with faces and biographical information, while undergoing functional magnetic resonance imaging (fMRI) of their brain activity. One week later, they undergo fMRI while recalling information in response loops that were previously paired or unpaired with face and biographical information. During both brain imaging sessions, rest periods provide opportunities for IRMI to occur. Analyses of the fMRI data are designed to identify brain areas separately representing the loops and the faces and bios, and to examine the communication between them during the different task conditions, to test the predictions that the coupling of these areas is stronger under conditions that enable binding of the musical and non-musical information, and that the coupling is stronger when those loops for which more IRMI has occurred are presented. Additional analyses are designed to identify loop-specific IRMI episodes during rest. This research develops our understanding of the relationship between two of the most common phenomena that people experience with music, and it provides further insights into mechanisms by which the human brain creates and consolidates memories. It may also help to explain why music serves as a potent cue for retrieving associated memories, even when memory structures of the brain involved in effortful memory retrieval are damaged, as in Alzheimer's disease.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R21</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of California, Davis</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=9883553&icde=52557910&ddparam=&ddvalue=&ddsub=&cr=1&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/impact-music-improvisation-training-brain-function-and-cognition-among-older-adults">7771</a>
Impact of Music Improvisation Training on Brain Function and Cognition among Older Adults
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/impact-music-improvisation-training-brain-function-and-cognition-among-older-adults"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon4_2.jpg?itok=WbuzZFAl" width="100" height="49" alt="" /></a></div></div></div>
Julene K Johnson, Charles Limb, Karen Barrett, Jennifer Bugos, Theresa Allison, and Jing Cheng
Julene K
Johnson
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Approximately 5.8 million adults age 60 and over in the United States live with Alzheimer disease and related dementias (AD/ADRD) at a cost of $290 billion per year. Older adults with mild cognitive impairment (MCI), an intermediate stage between typical aging and dementia, are 3-5 times more likely to progress to AD than those with normal cognition. Late-life engagement in cognitively challenging activities is associated with decreased risk of cognitive decline, and there is a need to address cognitive inactivity. Music interventions are a promising strategy to address late-life cognitive inactivity. Music training can change brain structure and function in non-musician adults, thereby leading to cognitive, perceptual, and psychosocial advantages. These changes in cognitive function are thought to occur because the multimodal, complex nature of music facilitates training-induced neural plasticity. However, the mechanisms are not yet understood, and most studies used traditional or rote keyboard training techniques. Music training based on improvisation principles—the spontaneous generation of musical melodies and rhythms—will likely have more potent effects on cognition and brain function. Improvisation facilitates cognitive flexibility, self-monitoring, novel idea generation, execution of unplanned motor sequences and entrance into a state of flow. Biologically, improvisation is associated with distinct neural patterns involving activation of prefrontal networks and other brain networks that are affected by aging. As a mechanism of behavior change, it is likely that improvisation training will uniquely improve self-regulation (the ability to monitor and control one’s own behavior, emotions, or thoughts and modify to situational demands). Yet, no research has tested whether improvisation training can improve self-regulation and facilitate maintenance of cognitively challenging activities among older adults with and without MCI. This project will develop and test the effects and mechanisms of a music improvisation training intervention on self-regulation of older adults with and without MCI. Our overall hypothesis is that improvisation training will lead to improvements in self-regulation, compared to controls, and that improvisation training will be associated with specific changes in prefrontal brain networks and ultimately cognitive engagement. Our project has two phases. In the R61 phase, we will develop a music improvisation training intervention that aims to improve self-regulation among older adults with and without MCI and conduct a 2-arm randomized pilot study to (i) examine feasibility and acceptability of the intervention and study methods and (ii) determine its effects on the hypothesized mechanism of self-regulation. If milestones are met, we will proceed to the R33 phase and conduct a randomized mechanistic trial to examine the effects of the intervention, compared to an attention control, on self-regulation and cognitive engagement among older adults with and without MCI. The findings from this study will improve our understanding of the underlying mechanisms of how music training interventions can facilitate behavior change to maintain health of older adults.</p>
<p>For more information on this project, see their <a href="https://reporter.nih.gov/project-details/10925727">NIH Research Portfolio</a>.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R61/R33</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of California, San Francisco</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><img alt="UCSF logo" height="112" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/ucsf.png" width="163" /></p>
</div></div></div>
<a href="/content/healing-attempt-digital-music-based-mindfulness-intervention-black-americans-elevated-race">12416</a>
healing attempt: a digital music-based mindfulness intervention for Black Americans with elevated race-based anxiety
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/healing-attempt-digital-music-based-mindfulness-intervention-black-americans-elevated-race"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon22.jpg?itok=g95IuUl-" width="100" height="49" alt="" /></a></div></div></div>
Grant Jones
Grant
Jones
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support studies assessing the impact and effectiveness of a digital music-based mindfulness intervention developed for Black American adults experiencing race-based anxiety. The project includes multiple, small-scale randomized-controlled trials (RCTs) and a mixed-methods implementation study, with the objectives of refining the intervention on an ongoing basis and assessing overall impact. The approximately half-hour session of music composition and production was developed using anxiety reduction principles, mindfulness practices, and meditation research, while also accounting for the race of the listener. It includes meditations, songs, and poetry rooted in Black American culture and music traditions, with themes relating to Black spirituality, belonging, and self-acceptance. As part of the implementation study, the intervention will be offered freely to the public, with participants accessing materials on music platforms and reporting experiences on the study's website. Content for the intervention will feature contributions from world renowned Black American artists and project collaborators, including esperanza spalding, Lama Rod Owens, and Terry Edmonds.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Harvard University</div></div></div>
<a href="/content/investigating-auditory-motor-interactions-during-rhythm-perception-small-animal-model">3666</a>
Investigating Auditory-Motor Interactions During Rhythm Perception in a Small Animal Model
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/investigating-auditory-motor-interactions-during-rhythm-perception-small-animal-model"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon13.jpg?itok=c-PIjpaA" width="100" height="49" alt="A person playing piano and brain icon on blue background" /></a></div></div></div>
Mimi Hsiao Feng Kao, PhD, Aniruddh Patel, PhD
Mimi
Kao, Aniruddh Patel
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Much of the world’s music has periodic rhythms with events repeating regularly in time, to which people clap, move, and sing. The ability to detect and predict periodic auditory rhythms is central to the positive effects of music-based therapies on a variety of neurological disorders, including improving phonological processing in dyslexia, enhancing language recovery after stroke, and normalizing gait in Parkinson’s disease. Yet the neural mechanisms underlying rhythm perception are not well understood, and progress is impeded by the lack of an animal model that allows precise measurement and manipulation of neural circuits during rhythm perception. Human neuroimaging studies indicate that perceiving periodic musical rhythms strongly engages the motor planning system, including premotor cortex and basal ganglia, even when the listener is not moving or preparing to move. Here, we test the hypothesis that the motor planning system is actively involved in learning to recognize temporal periodicity and communicates predictions about the timing of periodic events to the auditory system. We propose to take advantage of the well-described auditory-motor circuits in vocal learning songbirds and leverage the mechanistic studies possible in an animal model to test these ideas. Like humans (and unlike non- human primates), vocal learning birds have strong connections between motor planning regions and auditory regions due to their reliance on complex, learned vocal sequences for communication. Auditory-motor circuits in songbirds and humans have many structural and functional parallels. Recently, we showed that songbirds can readily learn to recognize a fundamental periodic pattern (isochrony, or equal timing between events) and can detect this pattern across a broad range of tempi. In Aim 1, we will test whether neural signals from premotor regions play a causal role in this ability to flexibly recognize periodic rhythms. In Aim 2, by recording in auditory cortex while reversibly silencing activity in a reciprocally connected premotor region, we will test whether premotor signals influence auditory processing of periodic rhythms. In Aim 3, by recording activity in a premotor region as birds learn to recognize isochrony as a global temporal pattern, we will determine whether premotor neurons develop sensitivity to temporal regularity and exhibit activity that predicts the timing of upcoming events. Establishing an animal model for rhythm perception will be transformative for music neuroscience, allowing detailed investigation of the neural mechanisms underlying rhythm perception and informing rhythm-based musical interventions to enhance function in normal and disease states.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R01</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Tufts University</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://reporter.nih.gov/search/bWOipKic5U-LzQdPhOpHQA/project-details/10564472">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/examining-how-youth-design-and-enact-their-social-educational-and-civic-futures-through-arts">10296</a>
Examining How Youth Design and Enact their Social, Educational, and Civic Futures through Arts, Activism, and Popular Culture
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/examining-how-youth-design-and-enact-their-social-educational-and-civic-futures-through-arts"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon23_1.jpg?itok=LKcNFB_s" width="100" height="49" alt="" /></a></div></div></div>
Lauren Kelly
Lauren
Kelly
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support an ethnographic case study of the role of hip-hop- based arts education in facilitating youth community-building, agency, and activism</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Rutgers University</div></div></div>
<a href="/content/decreasing-delirium-through-music-ddm-critically-ill-older-adults">1266</a>
Decreasing Delirium through Music (DDM) in critically ill older adults
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/decreasing-delirium-through-music-ddm-critically-ill-older-adults"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon14.jpg?itok=0YXbS0rq" width="100" height="49" alt="Decreasing Delirium through Music (DDM) in critically ill older adults" /></a></div></div></div>
Babar A Khan, MD
Babar
Khan, Linda Chlan
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>One million adults in the United States receive mechanical ventilation for acute respiratory failure in the intensive care units (ICUs) annually and up to 80% of them develop delirium during their ICU stay. Presence of delirium predisposes older adults to immediate in-hospital complications including a longer length of ICU and hospital stay, increased risk of in-patient mortality and elevated costs of care. In addition, ICU delirium is associated with long-term post-discharge complications such as development of cognitive impairment and dementia. Recent research studies exploring pharmacological strategies to manage ICU delirium have not demonstrated efficacy; a limitation also acknowledged in the Society of Critical Care Medicine 2018 Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption guidelines. Music listening is a non-pharmacological intervention that has shown to decrease over-sedation, anxiety and stress in critically ill patients, factors that could predispose to ICU delirium. We conducted a randomized pilot clinical trial, which showed that slow-tempo relaxing music could improve delirium/coma free days in mechanically ventilated critically ill patients. Our team is now proposing to conduct a large randomized clinical trial called “Decreasing Delirium through Music (DDM) in Critically Ill Older Adults to evaluate the efficacy of a seven-day slow-tempo music intervention on the primary outcome of delirium/coma free days among mechanically-ventilated older adults admitted to the ICU. The trial has the following aims: 1. Test the efficacy of music intervention in improving delirium/coma free days among mechanically ventilated patients as compared to attention control. 2. Test the efficacy of music intervention in improving delirium severity, pain and anxiety among mechanically ventilated patients as compared to attention control. 3. Test the efficacy of music intervention in improving the long-term neuropsychological outcomes as compared to attention control. Achievement of the aforementioned aims will provide an efficacious and scalable intervention to reduce delirium and improve brain health.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R01</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Indiana University-Purdue University at Indianapolis</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10016165&icde=52557690&ddparam=&ddvalue=&ddsub=&cr=2&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/evaluating-impact-singing-interventions-markers-cardivascular-health-older-patients">1271</a>
Evaluating the Impact of Singing Interventions on Markers of Cardivascular Health in Older Patients with Cardiovascular Disease
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/evaluating-impact-singing-interventions-markers-cardivascular-health-older-patients"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon15.jpg?itok=GA27z_Kv" width="100" height="49" alt="Evaluating the Impact of Singing Interventions on Markers of Cardivascular Health in Older Patients with Cardiovascular Disease" /></a></div></div></div>
Jacquelyn Kulinski, MD
Jacquelyn
Kulinski
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Cardiovascular disease (CVD) claims more lives each year than cancer and chronic respiratory disease combined. Participation in cardiac rehabilitation (CR) reduces mortality and risk of a major cardiovascular event in secondary prevention populations, including older adults. Older adults are less likely to participate in CR, as comorbidities in this population, including arthritis and chronic obstructive pulmonary disease, make participation difficult. Singing is a physical activity that involves components of the vagal nerves manifested as changes in cardiac autonomic regulation. Unlike physical exercise, the effects of singing on cardiovascular health has not been well-studied. To our knowledge, no studies have evaluated the impact of singing on important cardiac biomarkers. Our hypothesis is that older patients with CVD will have favorable improvement in cardiovascular biomarkers, including, endothelial function and heart rate variability (HRV), after 30 minutes of singing. Our pilot data in 23 subjects provides proof of principle, with a small, but significant, improvement in peripheral vascular endothelial function (measured by peripheral arterial tonometry) after 10 minutes of singing. This pilot study has helped us optimize the clinical trial design for this proposal, which will include a more targeted population, incorporation of personal music preferences, increased duration of singing, inclusion of a music therapist and measurement of brachial artery flow-mediated dilation (FMD), the “gold standard” measurement for vascular endothelial function, as our primary outcome. Our proposal seeks to create, optimize and test two different singing interventions in older patients with CVD. The study will consist of three arms, according to a randomized, single-blind, crossover, sham procedure-controlled design. Sixty-five total participants will each have three visits on three different occasions for the following interventions: (1) a 30-minute period of guided singing from an in- person music therapist, (2) a 30-minute period of singing along to an instructional video including a professor of voice and “inexperienced, older singing student” and (3) a 30-minute rest period without any intervention. We will use biofeedback (target heart rate and BORG Rating of Perceived Exertion) to help subjects optimize the cardiovascular impact of the music interventions. The (2-year) R61 phase of this proposal will assess the feasibility (implementation, practicality, and acceptability) of executing the proposed study design (Aim 1). We anticipate that the R33 phase will take 3 years to complete. The combined R61/R33 phases will be statistically powered to assess changes in FMD and HRV (primary and secondary outcomes, Aims 2a and 2b). An alternative mechanism in Aim 3 will explore the impact of singing on mental health and well-being by measuring salivary cortisol and cytokines and by using a validated visual mood score designed to evaluate performing arts activities in healthcare settings. We will determine which singing intervention, if any, is superior to the other – as this would be important to guide longer and larger clinical trials in the field. Knowledge gained from this proposal will improve our understanding of biologic mechanisms of singing behaviors, as it relates to CVD.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R61</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Medical College of Wisconsin</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10016830&icde=52557735&ddparam=&ddvalue=&ddsub=&cr=1&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/recovery-icu-investigation-music-induced-physiologic-and-metabolic-changes-promote-healing">5106</a>
Recovery in the ICU: An Investigation of Music-induced Physiologic and Metabolic Changes that Promote Healing
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/recovery-icu-investigation-music-induced-physiologic-and-metabolic-changes-promote-healing"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon2_0.jpg?itok=Vb2StnPk" width="100" height="49" alt="Recovery in the ICU: An Investigation of Music-induced Physiologic and Metabolic Changes that Promote Healing" /></a></div></div></div>
Julia Langley, Jagmeet Kanwal
Julia
Langley, Jagmeet Kanwal
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study examining whether and how listening to musical performances in an intensive care unit (ICU) can improve patient recovery and healing. Researchers from Georgetown University Medical Center's Lombardi Arts and Humanities Program and Neurophysiology and Behavior Laboratory will team with the Anesthesiology Unit at MedStar Georgetown University Hospital to test the hypothesis that music can promote healing by altering the mental and physiological profile of ICU patients. Physiologic measures will include blood pressure, respiration rate, pulse rate, ventilation rate and volume, and blood oxygen saturation levels; and salivary measures of cortisol, dopamine, and oxytocin levels.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Georgetown University</div></div></div>
<a href="/content/investigating-neural-mechanisms-underlying-language-recovery-through-rhythm-therapy-aphasia">3671</a>
Investigating the neural mechanisms underlying language recovery through rhythm therapy in aphasia
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/investigating-neural-mechanisms-underlying-language-recovery-through-rhythm-therapy-aphasia"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon16.jpg?itok=zs-V6ue8" width="100" height="49" alt="Investigating the neural mechanisms underlying language recovery through rhythm therapy in aphasia" /></a></div></div></div>
Yune S Lee, PhD
Yune
Lee
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Every year, approximately 100,000 people are diagnosed with aphasia—a language disorder leading to substantial difficulties in their daily communication. Based on the observation that many people with aphasia can sing words that they otherwise cannot speak, melodic intonation therapy (MIT) was developed in the 1970s. Although recognized as a standard aphasia treatment, the neural mechanisms of MIT have been largely unexplored. Our first goal is to identify the active ingredient of this music-based intervention that leads to language recovery. Although rhythm has long been considered secondary to melody, recent evidence has challenged this notion by demonstrating that rhythm alone is sufficient enough to facilitate improvements in speech fluency for people with aphasia. To corroborate the faciliatory role of rhythm, we will train aphasic patients to leverage “rhythm” for sets of sentences/phrases delivered through a fun and engaging video gaming platform. This intervention emerges from the theoretical framework, built from neuroimaging data, that language processes heavily rely on neural resources within the sensorimotor and fronto-striatal circuits that subserve rhythm/timing processes. Our second goal is to characterize the neural plasticity associated with language recovery promoted by the novel rhythm-based therapy. We hypothesize that neuroplasticity will manifest itself as increased white matter tracts, presumably due to changes in myelination in either ipsilateral or contralateral (homologues) language areas. To effectively measure myelin white matter fraction (MWF) in candidate tracts, we will mainly use a patented Myelin-imaging technique. Additionally, we will measure resting-state functional connectivity using BOLD (Blood Oxygen- Level Dependent) fMRI. Lastly, we will attempt to record cortical activity using fNIRS (functional Near-Infrared Spectroscopy) during the pre-post behavioral assessments. Taken together, the proposed interdisciplinary research has theoretical, methodological, and clinical innovations and significance. This exploratory work will serve as a critical stepping stone toward unraveling the therapeutic component of music in neurological disorders and will provide evidence-based guidance to the clinicians and therapists.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R21</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Texas, Dallas</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10250678&icde=52557979&ddparam=&ddvalue=&ddsub=&cr=1&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/music-interventions-children-and-families-social-emotional-development-and-well-being">3616</a>
Music Interventions for Children and Families: Social-Emotional Development and Well-Being
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/music-interventions-children-and-families-social-emotional-development-and-well-being"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon17.jpg?itok=4q5gpwwA" width="100" height="49" alt="Child development" /></a></div></div></div>
Miriam Lense, PhD
Miriam
Lense
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Vanderbilt University Medical Center will conduct studies in partnership with Treatment and Research Institute for Autism Spectrum Disorders, Nashville Symphony Orchestra, Nashville Opera, and VSA Tennessee, the state organization on the arts and disability. One set of studies include a randomized-waitlist control trial of a community-based music program (named SeRenade) designed to foster active engagement of parents and children with autism through shared musical experiences; follow up studies aim to test whether child and parent outcomes vary by treatment type: individual parent-child music training only, SeRenade only, and combining individual training with the SeRenade program. Separate studies include a national survey of music engagement by families with and without autistic children, and a study that highlights the impact of psychoeducational songwriting for the well-being of parents with children who have developmental disabilities. VUMC will host a quarterly Music Research Forums to promote the development and refinement of the Lab studies, as well as design a publicly available, manualized music-based curriculum for children with developmental disabilities and their parents.</p>
<p>The research agenda will address the following research questions:</p>
<ul>
<li>What are the social and emotional benefits of a therapeutic music program for children with and without Autism Spectrum Disorder (ASD) and for their parents?;</li>
<li>What are the mechanism of action and group dynamics by which music engagement improves social and emotional well-being and builds empathy and acceptance among families with and without ASD?; and</li>
<li>How does musical engagement differ in a large, national sample including families of children with and without developmental, medical, and mental health conditions?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Vanderbilt University Medical Center</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Pablo Juárez, MEd</li>
<li>Mark Wallace, PhD</li>
<li>Elizabeth May Dykens, PhD</li>
</ul>
</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this Lab, see their <a href="https://www.vumc.org/music-cognition-lab/nea-research-lab" target="_blank">Research Lab webpage</a>.</p>
</div></div></div>
<a href="/content/musical-rhythm-sensitivity-scaffold-social-engagement-autism-spectrum-disorder">3646</a>
Musical Rhythm Sensitivity to Scaffold Social Engagement in Autism Spectrum Disorder
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/musical-rhythm-sensitivity-scaffold-social-engagement-autism-spectrum-disorder"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon18.jpg?itok=k7fHpYYk" width="100" height="49" alt="Music and child development" /></a></div></div></div>
Miriam Lense, PhD
Miriam
Lense
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>We recently demonstrated that a critical infant adaptive social behavior -- looking into the eyes of an engaging caregiver -- obeys a fundamental biological principle of ‘entrainment’: Infant eye-looking entrains (or becomes time-locked) to the rhythmic social cueing of a caregiver during social musical interactions of infant-directed singing. Equally importantly, caregivers structure their own child-directed behavior to enhance this rhythmic cuing and facilitate the delivery and receipt of meaningful social information. These results inform basic mechanisms of typical social development as well as disruptions in social development in children with ASD. A common and lifelong neurodevelopmental disorder, individuals with ASD exhibit impairments in social and communicative functioning that require specialized support. In pilot data for the current proposal, we observe that toddlers with ASD show attenuated, though present, rhythmic entrainment to predictable child-directed singing. The current project builds upon our findings of rhythmic social entrainment during infancy to advance mechanistic understanding of rhythmic entrainment in social development in typically developing toddlers and those with ASD, as well as propose rhythmic entrainment as an active ingredient of music-based interventions for social communication in toddlers with ASD. In the R61, we first quantify the effects of rhythmic entrainment to child- directed singing in toddlers with and without ASD (R61 Aim 1) and examine predictability as a driver of this entrainment (R61 Aim 2). Successfully establishing rhythmic entrainment during predictable social musical engagement (Go/No-Go criteria) will provide strong evidence of a potential fundamental role of rhythm sensitivity in social entrainment. In the R33, we measure the extent to which individual levels of rhythmic entrainment in ASD are mechanistic predictors of response to music-enhanced and standard evidence-based naturalistic developmental behavioral interventions for ASD (R33 Aim 3). Establishing malleability in social rhythm sensitivity is a crucial step for identifying potential mechanisms of change for future investigations of music-based treatments for functional social communication outcomes in ASD. In alignment with RFA-AT-19-001, Promoting Research on Music and Health, this project will facilitate rigorous studies of child health and development and musical interventions. Through examination of the principles of social entrainment afforded by natural social musical interactions, this research has implications for basic mechanisms of disrupted interpersonal synchrony in ASD, while also identifying potential targets of active engagement for the development of music-based interventions.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R61</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Vanderbilt Medical Center</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10016775&icde=52557787&ddparam=&ddvalue=&ddsub=&cr=2&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/neural-substrates-improvisation-across-different-artistic-domains">3611</a>
Neural Substrates of Improvisation Across Different Artistic Domains
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/neural-substrates-improvisation-across-different-artistic-domains"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon19.jpg?itok=of47zuCN" width="100" height="49" alt="Music training and brain" /></a></div></div></div>
Charles Limb, MD, Karen Barrett, PhD
Charles
Limb, Karen Barrett
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The Sound and Music Perception Lab at the University of California, San Francisco will conduct studies to identify neural substrates for creativity across a range of art forms. This lab's principal activity will involve collecting and analyzing data from "genius improvisers" in music, the visual arts, and comedy. Participants in these three art forms will perform an improvisational task, compared with an appropriate control task, while their brains are scanned with a functional magnetic resonance imaging (fMRI) device. In addition, participants will complete a battery of assessments, including personality measures, tests of creativity, and tests of cognitive abilities. Researchers will work with SF Jazz, The San Francisco Art Institute, Second City Improvisation Troupe, and Speechless to design experimental tasks suitable for each artistic domain and will help recruit participants. The studies will serve as proof-of-concept for studying improvisation across artistic domains.</p>
<p>The research agenda aims to address the following research questions:</p>
<ul>
<li>What is the relationship between one or more forms of arts participation and other forms of creativity?; and</li>
<li>What are the cognitive and/or social processes of arts-based creativity, and how do they affect learning-related outcomes?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of California, San Francisco</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this Lab, see their <a href="https://ohns.ucsf.edu/limb-lab">Research Lab webpage</a>.</p>
<p><img alt="UCSF logo" height="112" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/ucsf.png" width="163" /></p>
</div></div></div>
<a href="/content/amend-assessment-music-experiences-navigating-depression">10896</a>
AMEND: Assessment of Music Experiences in Navigating Depression
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/amend-assessment-music-experiences-navigating-depression"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon25_4.jpg?itok=quFLcCE3" width="100" height="49" alt="" /></a></div></div></div>
Joanne Loewy
Joanne
Loewy
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The Assessment of Music Experiences in Navigating Depression (AMEND) lab at Mount Sinai Health System's Louis Armstrong Center for Music and Medicine, in partnership with Carnegie Hall's Weill Music Institute, will measure the social-emotional benefits of music participation in individual and group settings, specifically for individuals across the lifespan and who have clinical depression. Subpopulations of interest are children, teens, and college students; first-time parent(s) of pre-term infants; and older adults with neurologic diseases.</p>
<p>Using mixed-methods research approaches, the lab will conduct a series of studies examining the impact of music through various modes of engagement, including music concerts and music therapy sessions. Comparison-group studies of standard care without music engagement also will be conducted. Pre- and post-intervention data will be collected from participants on outcomes such as depression and resilience, mood and affect, sleep quality, and quality of life. Additional data will be collected to understand contextual factors such as participants' prior levels of experience working with music.</p>
<p>Planned research products include a lab website, recordings of "well-being" music concerts held for the participants, research articles, conference presentations, and a standardized assessment tool and manual that will inform creative arts therapists and other healthcare professionals about the impacts that music engagement may have for depression. Additional partners include Cooper Union, Third Street Music School, Young Adults Institute, and Lincoln Center Moments.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Icahn School of Medicine at Mount Sinai</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Angela Diaz</li>
<li>Manuel Bagorra</li>
<li>Nthan Goldstein</li>
</ul>
</div></div></div>
<a href="/content/multimodal-musical-stimulation-healthy-neurocognitive-aging">10311</a>
Multimodal Musical Stimulation for Healthy Neurocognitive Aging
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/multimodal-musical-stimulation-healthy-neurocognitive-aging"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon15_4.jpg?itok=SJulHLpS" width="100" height="49" alt="" /></a></div></div></div>
Psyche Loui
Psyche
Loui
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Music that we encounter every day contains amplitude and frequency modulations, rapid changes in acoustic signals that convey meaningful information to the listener. The human brain’s ability to receive and interpret meaning from these signals is implemented by networks of neural oscillations: firing patterns of groups of neurons that track the music with rhythmic activity. Neural oscillations in different frequency bands subserve attention and memory, as well as perception and comprehension; they develop over the lifespan and are reduced in aging, especially in dementia. Being able to understand and causally control neural oscillations will have crucial implications for healthy neurocognitive aging. Since music naturally stimulates the brain with its rhythmic content over time, we hypothesize that music can be used as a sustainable, naturalistic form of brain stimulation to induce oscillatory in neuronal populations. Furthermore, we hypothesize that by inserting gamma-band energy as sensory stimulation during music listening, we can increase gamma-band activity in the brain in a way that is frequency-tuned to the brain’s intrinsic network dynamics, thus replacing the decreased neural oscillations that are reduced in aging, and improving memory and cognition in older adults. We hypothesize that gamma-band modulations inserted in lights, when coupled with music listening, can improve memory in older adults by frequency-tuning to intrinsic individual brain network dynamics. Here we propose the first randomized, double-blind, placebo-controlled feasibility study, to test the effects of music-coupled gamma-band stimulation on EEG and behavioral indices of working memory in older adults. Results will test the causal role of oscillatory mechanisms of the brain on cognition. If successful, this trial will lay the groundwork to the first musical, neurophysiologically targeted, brain-stimulation device for reversing cognitive decline in aging.</p>
<p>For more information on this project, see their <a href="https://reporter.nih.gov/project-details/10584522">NIH Research Portfolio</a>.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R21</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Northeastern University</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Edward Large</p>
</div></div></div>
<a href="/content/effects-music-training-auditory-processing-and-high-frequency-hearing-abilities-adolescent">3676</a>
Effects of Music Training on Auditory Processing and High-Frequency Hearing Abilities in Adolescent Musicians
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/effects-music-training-auditory-processing-and-high-frequency-hearing-abilities-adolescent"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon20.jpg?itok=TfXRF0G6" width="100" height="49" alt="Effects of Music Training on Auditory Processing and High-Frequency Hearing Abilities in Adolescent Musicians" /></a></div></div></div>
Anne E Luebke, PhD
Anne
Luebke
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>The aims of this research proposal are to provide a definitive answer to the question of whether formal musical training is associated with enhanced perception of sound. Musicians have been reported to possess enhanced auditory processing of sounds both in quiet and in noise – a result of processes that may begin as early in the auditory pathway as the cochlea itself. These enhancements may underlie improved abilities to understand speech-in-noise, and because of their profound implications, these studies have generated tremendous interest. However, many of the conclusions were based on studies that had i) relatively few participants, ii) mostly adult participants and iii) no assessment of audiometric or cochlear function in the extended high-frequency (EHF) ranges. These proposed experiments are aimed to remedy these deficiencies by recruiting 150 youth musicians, and assessing both audiometric and cochlear EHF regions. Interestingly, even in people with clinically normal hearing thresholds there are differences in hearing in noise abilities. In fact, while there is no clear relationship between normal standard thresholds (0.25-8kHz) and hearing in noise abilities, there is a proposed relationship between extended high-frequency (EHF) hearing thresholds (8-20 kHz) and improved hearing in noise abilities. In addition to audiometric EHF thresholds, cochlear outer hair cell health can also be assessed non-invasively using distortion-product otoacoustic emissions (DPOAEs) both in the standard and EHF frequency ranges. As mentioned early, most previous studies have sorted their adult participants into “musicians” or “non- musicians” based on years of musical training. Our laboratory has recently shown (in both children and adults) that musical aptitude and musical training significantly predict hearing-in-noise abilities. Our hypothesis is that this `musician advantage' in auditory processing is related to both EHF cochlear function and musical aptitude. For both aims, we will recruit ~150 youth (11-18 years) who are students at The Hochstein School as well as other area youth musicians. The Hochstein School enrolls ~ 715 students/year in this age range in their classes and ensembles, providing a natural recruitment platform to assess these behavioral and physiological measures. The specific aims are to investigate whether the `musician advantage' in auditory processing is related to i) EHF audiometric and cochlear function and ii) musical aptitude. Information gained from these studies in youth musicians will provide a rigorous assessment of whether the `musician advantage' in auditory processing exists for all types of sound, and if this advantage is related to musical aptitude, musical training, and EHF cochlear health. We will also be examining what extent music and speech hearing-in-noise abilities overlap, and will be establishing norms and outcome measures that can be used to assess future music-based interventions.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R21</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Rochester</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10017174&icde=52557996&ddparam=&ddvalue=&ddsub=&cr=3&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/c-sharp-b-sharp-evaluating-arts-enrichment-programming-people-dementia-and-their-caregivers">4971</a>
C Sharp B Sharp: Evaluating arts enrichment programming for people with dementia and their caregivers
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/c-sharp-b-sharp-evaluating-arts-enrichment-programming-people-dementia-and-their-caregivers"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon14_0.jpg?itok=J5oUaz7d" width="100" height="49" alt="C Sharp B Sharp: Evaluating arts enrichment programming for people with dementia and their caregivers" /></a></div></div></div>
Laura Malinin
Laura
Malinin
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a series of cross-disciplinary, mixed-method studies examining the cognitive, physiological, and social benefits of live performing arts attendance for older adults with cognitive impairment and for their caregivers. The B Sharp Art Works program will provide symphony, dance, or theater season tickets for older adults exhibiting mild to severe cognitive decline and to their caregivers; they will attend performances during a six-month period. The quasi-experimental research project uses a waitlist-control group to isolate the effects of different types of performing arts experience (music, dance, and theater). Primary data will be collected from pre- and post-assessments; direct observations; continuous physiological measures such as heart rate, activity rate, and sleep patterns; surveys; and interviews. Researchers will assess changes in cognition and social behaviors affecting quality of life for older adults with cognitive impairment and for their caregivers.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Colorado State University</div></div></div>
<a href="/content/examining-effects-music-imagery-and-movement-mim-treatment-intervention-emotional-and">8491</a>
Examining the effects of the Music, Imagery, and Movement (MiM) treatment intervention on emotional and cognitive functioning of residents in long-term care
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/examining-effects-music-imagery-and-movement-mim-treatment-intervention-emotional-and"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon1_1.jpg?itok=6ExnJtmR" width="100" height="49" alt="" /></a></div></div></div>
Holly Matto
Holly
Matto
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a randomized, waitlist-controlled trial examining the effects of visual arts, music, and dance therapy on the emotional and cognitive functioning of older adults. The study will occur in a long-term care facility housing low-income, older adults from diverse racial and ethnic backgrounds. Trained facilitators will engage older adults in a music, imagery, and movement (MiM) intervention, or, alternatively, in social group interaction. The study will include surveys and observational and clinical assessments, focus groups, and structured interviews, along with pre- and post-therapy measurements.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">George Mason University</div></div></div>
<a href="/content/colorado-resiliency-arts-lab-coral">3621</a>
Colorado Resiliency Arts Lab (CORAL)
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/colorado-resiliency-arts-lab-coral"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon21.jpg?itok=RJ12q5Mn" width="100" height="49" alt="Music and creativity" /></a></div></div></div>
Marc Moss, MD
Marc
Moss
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>As part of its research agenda, University of Colorado Denver will develop and test a series of creative arts therapy programs designed to build resilience among critical care health professionals. The programs will use qualitative, mixed-method, and randomized controlled study designs and will integrate visual arts therapy, music therapy, dance/movement therapy, and writing/poetry therapy. Research activities will include focus groups of important stakeholders, such as critical care providers, intensive care unit managers and hospital administrators, and national critical care leadership. Organization partners include Ponzio Creative Arts Therapy Program at Children's Hospital Colorado and Lighthouse Writers Workshop; these organizations will help to design experimental tasks suitable for each artistic domain and will aid in recruiting participants. Future directions may include studying longer-term treatment effects of creative arts therapies for health care professionals as well as the indirect effects such programs have on patient outcomes.</p>
<p>The research agenda will address the following research questions:</p>
<ul>
<li>What changes in physical or mental health outcomes are experienced by subjects receiving creative arts therapies?; and</li>
<li>What are the comparative therapeutic benefits of creative arts therapies relative to each other or to non-arts-based interventions?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Colorado Denver</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Tony Edelblute, LPC, MT-BC</li>
</ul>
</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this Lab, see their <a href="https://medschool.cuanschutz.edu/coral">Research Lab webpage</a>.</p>
<p><img alt="University of Colorado Denver logo" height="53" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/CU-Denver.png" width="225" /></p>
</div></div></div>
<a href="/content/impact-performing-arts-attendance-cognitive-health-and-wellbeing-older-adults-0">8511</a>
The Impact of Performing Arts Attendance on the Cognitive Health and Wellbeing of Older Adults
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/impact-performing-arts-attendance-cognitive-health-and-wellbeing-older-adults-0"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon14_2.jpg?itok=VPmk2m3x" width="100" height="49" alt="" /></a></div></div></div>
Rekha Rajan
Rekha
Rajan
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study of the relationship between live performing arts attendance (concerts, plays, or musicals) and changes in the stress levels and cognitive ability of older adults. To be conducted in partnership with Rush University Medical Center, the study will use data from the Chicago Health and Aging Project, a longitudinal study of health concerns, especially risk factors for Alzheimer's disease, in African Americans and white Americans aged 65 years and older.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Concordia University Chicago</div></div></div>
<a href="/content/biologic-mechanisms-and-dosing-active-music-engagement-manage-acute-treatment-distress-and">3651</a>
Biologic Mechanisms and Dosing of Active Music Engagement to Manage Acute Treatment Distress and Improve Health Outcomes in Young Children with Acute Lymphoblastic Leukemia
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/biologic-mechanisms-and-dosing-active-music-engagement-manage-acute-treatment-distress-and"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon24.jpg?itok=7cYpYUWB" width="100" height="49" alt="Biologic Mechanisms and Dosing of Active Music Engagement to Manage Acute Treatment Distress and Improve Health Outcomes in Young Children with Acute Lymphoblastic Leukemia" /></a></div></div></div>
Sheri Lynn Robb, PhD, MT-BC
Sheri
Robb
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Music therapy has become a standard palliative care service in many pediatric and adult hospitals. However, a majority of music therapy research has focused on the use of music to improve psychosocial dimensions of health, without considering biological dimensions. In addition, few studies have examined dose-response relationships. Cancer treatment is an inherently stressful experience, and a significant number of young children and parents (caregivers) experience persistent, interrelated emotional distress and poor quality of life. Many parents also experience traumatic stress symptoms because of their child's cancer diagnosis and treatment. Our previously tested Active Music Engagement (AME) intervention uses active music play to diminish stressful attributes of cancer treatment to help manage emotional/traumatic distress experienced by young children (ages 3-8) and parents and improve quality of life. A recent AME trial is examining psychosocial mechanisms of action responsible for change in child/parent outcomes. The current study expands on this work by examining AME's effects on several biomarkers to povide a more holistic understanding about how active music interventions work to mitigate cancer-related stress and its potential to improve immune function. The purposes of this two group, randomized controlled trial are to examine biological mechanisms of effect and dose-response relationships of AME on child/parent stress during the consolidation phase of Acute Lymphoblastic Leukemia (ALL) treatment. Specific aims are to: 1) establish whether AME lowers child and parent cortisol, 2) examine cortisol as a mediator of AME effects on child and parent outcomes, and 3) examine the dose-response relationship of AME on child and parent cortisol. Child/parent dyads (n=228) will be stratified (by age, site, ALL risk level) and randomized in blocks of four to AME or attention control. Each group will receive one 45-minute session during weekly clinic visits for the duration of ALL consolidation (4 weeks standard risk; 8 weeks high risk). Parents will complete measures at baseline and following the last study session. Child and parent salivary cortisol samples will be taken pre and post-session for the first 4 AME or attention control sessions. Child blood samples will be reserved from routine blood draws prior to sessions 1 and 4 (all participants) and session 8 (high risk participants). Linear mixed models will be used to estimate AME's effect on child and parent cortisol. Examining child and parent cortisol as mediators of AME effects on child and parent outcomes will be performed in an ANCOVA setting, fitting the appropriate mediation models using MPlus and then testing indirect effects using the percentile bootstrap approach to estimate the indirect effect. Graphical plots and non-linear repeated measures models will be used to examine the dose-response relationship of AME on child and parent cortisol. Findings will increase mechanistic understanding of the effects of active music interventions on multiple biomarkers and understanding of dose-response effects, with direct implications for the evidence-based use of music to improve health.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R01</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Indiana University-Purdue University at Indianapolis</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10021459&icde=52557833&ddparam=&ddvalue=&ddsub=&cr=5&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
</div></div></div>
<a href="/content/noisy-life-musician-implications-healthy-brain-aging">10316</a>
The Noisy Life of the Musician: Implications for Healthy Brain Aging
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/noisy-life-musician-implications-healthy-brain-aging"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon15_5.jpg?itok=UZMrMj16" width="100" height="49" alt="" /></a></div></div></div>
Erika Skoe
Erika
Skoe
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Playing a musical instrument is a popular childhood and adult activity with documented health benefits. One of the most provocative, but least understood, proposed health benefits is preserved brain function in advanced age. Playing a musical instrument, however, can also pose significant health hazards, including those that come from routine exposure to noisy (loud) environments. Beyond the risks of hearing loss from loud environments, noise exposure is a significant risk factor for age-related functional declines. While both the benefits and risks of musical training have been widely studied, little attention has been given to their interplay. To understand the mechanisms that mediate the effects of musical training on the human brain, we must develop a more complete accounting of the risk factors that could counteract the benefits of musical training and the degree to which benefits persist in the face of these risks. To more fully harness the therapeutic benefits of music, we also need a better account of whether the benefits persist after a musician stops playing their instrument. These knowledge gaps motivate the proposed work on auditory brain aging, in which lifelong musicians will be compared to controls and to ex-musicians who have not played a musical instrument since childhood. The proposed work is grounded in our published studies of auditory brain aging, and our published and pilot studies on the interplay of musical training and noise exposure on the young adult auditory brain. The proposed work aims (1) to characterize current and lifetime noise exposure from music and non-music activities, (2) to investigate relations among lifelong musical training, lifetime noise exposure, and auditory-brain aging, and (3) to investigate relations between childhood musical training and later-life auditory-brain function. For all three aims, young adults (18- 24 years) will be compared to middle-aged adults (45-60 years). We hypothesize that music, as a form of acoustic enrichment and training, may mitigate the impact of noise injuries and age-related decline by strengthening the neural systems most vulnerable to being compromised. Our methodological approach is innovative, comprehensive, and corroborated by our prior work. We will use a novel combination of personal sound dosimetry and structured interviews to characterize the risk of noise injury. Noise exposure data will be combined with validated methods to study auditory brain aging across multiple neural circuits, using a statistical design that accounts for selection bias and confounding variables such as socioeconomic status and cochlear function. Most studies of human auditory aging focus on older adults (60+ years), with less attention on studying early-stage aging when opportunities for the prevention of functional decline are greater. This motivates our decision to focus on early-stage aging. The outcomes of this work may suggest new approaches to promote healthy brain aging and clinical recommendations about harnessing the therapeutic properties of music training to maximize benefits and minimize hazards. Our multidisciplinary study team has complementary expertise in auditory neuroscience (Skoe), noise exposure (Tufts), biostatistics (Harel), and aging (Kuchel).</p>
<p>For more information on this project, see their <a href="https://reporter.nih.gov/project-details/10659111">NIH Research Portfolio</a>.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R01</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Connecticut</div></div></div>
<a href="/content/evaluating-effects-music-education-programming-low-income-communities-longitudinal">4996</a>
Evaluating the effects of music education programming in low-income communities: A longitudinal randomized control study assessing executive function and social emotional development
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/evaluating-effects-music-education-programming-low-income-communities-longitudinal"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon17_0.jpg?itok=V5wQOmS0" width="100" height="49" alt="Evaluating the effects of music education programming in low-income communities: A longitudinal randomized control study assessing executive function and social emotional development" /></a></div></div></div>
Jessica Smokoksi
Jessica
Smokoksi
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a randomized controlled study assessing the effects of orchestral programming on youth. The study will track the impact of this programming on students' social-emotional development, executive function (a set of mental skills that include working memory, flexible thinking, and self-control), and academic performance. Furthermore, the study will expand an ongoing randomized controlled study so that kindergarteners and first graders can be tracked beyond one year of program participation. Additional research topics will include: the degree to which consistent youth music programming affects parental or familial outcomes for educational involvement, in terms of practice, self-efficacy, and social capital development; how outcomes from the programming vary by youths' race/ethnicity, gender, family income level, and by school; how outcomes vary or emerge based on length of program participation and/or across years; and how music programming participation may have a potential protective factor with regards to coronavirus-related challenges. For this study, the Social Science Research Institute at Duke is partnering with Kidznotes, a multi-site, El Sistema-inspired program serving Durham and Wake counties in North Carolina. </p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Duke University</div></div></div>
<a href="/content/epiarts-lab-university-florida">1241</a>
EpiArts Lab at the University of Florida
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/epiarts-lab-university-florida"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon25.jpg?itok=a24J_kE8" width="100" height="49" alt="Music and population health" /></a></div></div></div>
Jill Sonke, PhD
Jill
Sonke
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>In partnership with the UF Health Shands Arts in Medicine program and the University College of London, the University of Florida's Center for Arts in Medicine will develop an "EpiArts" Lab to apply epidemiological research approaches to the arts. The Lab will plan and implement a long-term research agenda to explore the relationships between arts/cultural engagement and population health outcomes. Researchers will analyze several large-cohort, longitudinal, and publicly available datasets such as those sponsored by the National Center for Education Statistics, and datasets from the Health and Retirement Study and the General Social Survey—both featuring arts and cultural survey items developed by the Arts Endowment. To the extent possible, research questions will consider how arts engagement uniquely contributes to health, above and beyond other types of non-arts engagement. The Lab initially will focus its review on the arts' relationships to mental health and well-being, health behaviors, and non-communicable diseases. Additional research may include targeted experimental studies. Products stemming from the Lab may include peer-review publications, conference presentations, webinars, and infographics to translate the Lab's results to the general public and to leaders in the arts/cultural and health sectors.</p>
<p>The research agenda aims to address the following research questions:</p>
<ul>
<li>What are the social, emotional, physical, and/or physiological health benefits of participating in the arts for individuals, groups, or societies?</li>
<li>What physiological or psychological mechanisms or group dynamics are at work in achieving those benefits or related outcomes?</li>
<li>What kinds of art forms are invoked in these relationships, and at what levels of participation? d. How do these benefits or related outcomes vary by one's age, socioeconomic characteristics, other demographic and behavioral patterns, and/or by health or disability status?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Florida, Gainesville</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Daisy Fancourt, PhD</li>
</ul>
</div></div></div>
<a href="/content/emergency-music-project">8506</a>
The Emergency Music Project
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/emergency-music-project"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon7_0.jpg?itok=UBM3XcGc" width="100" height="49" alt="" /></a></div></div></div>
Jill Sonke
Jill
Sonke
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study of the effects of live preferential music on emergency department operations. The randomized, controlled study will use a group of professional musicians to serve in an emergency and level-one trauma care setting. Researchers will examine whether patients who are guided by the musicians to select live music options show higher levels of satisfaction, less reliance on pain medications, reduced hospital stays, and lower overall costs of care when compared with patients who do not have the opportunity to select live music options. Staff who are exposed to the music also will be assessed for perceptions of personal work performance and satisfaction in the workplace.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Florida</div></div></div>
<a href="/content/exploring-mechanisms-group-singing-persons-parkinson%E2%80%99s-disease">5116</a>
Exploring the mechanisms of group singing in persons with Parkinson’s disease
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/exploring-mechanisms-group-singing-persons-parkinson%E2%80%99s-disease"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon4_1.jpg?itok=wxHOPkFf" width="100" height="49" alt="Exploring the mechanisms of group singing in persons with Parkinson’s disease" /></a></div></div></div>
Elizabeth Stegemoller
Elizabeth
Stegemoller
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a study of the underlying mechanisms by which music may improve motor function in adults with Parkinson's disease. Clinical and related outcome measures will be taken before and after eight weeks of a non-arts intervention and after eight and sixteen weeks of group singing. Researchers hypothesize that group singing will yield improvements in clinical motor symptoms and positive changes in cortisol and inflammatory markers, and improvements in voice, breath control, and ability to swallow. The study also will analyze the relationships between motor symptoms and stress and brain activity in these adults. Additional assessment data will derive from a healthy group of adults without Parkinson's disease. The study results will contribute to a growing body of evidence about the potential benefits of music-based interventions for adults with Parkinson's disease.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Iowa State University of Science and Technology</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>Marian Kohut</li>
<li>Elizabeth Shirtcliff</li>
</ul>
</div></div></div>
<a href="/content/stories-and-songs-incarceration-equity-justice-and-community-impact-interdisciplinary-arts">5091</a>
Stories and Songs of Incarceration, Equity, Justice, and Community: Impact of an Interdisciplinary, Arts-Based Project on Formerly Incarcerated Persons, Pre-Service Students, and Community Members
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/stories-and-songs-incarceration-equity-justice-and-community-impact-interdisciplinary-arts"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon12_0.jpg?itok=rkTLoTlU" width="100" height="49" alt="Stories and Songs of Incarceration, Equity, Justice, and Community: Impact of an Interdisciplinary, Arts-Based Project on Formerly Incarcerated Persons, Pre-Service Students, and Community Members" /></a></div></div></div>
David Stringham
David
Stringham
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a mixed-methods study examining potential impacts of an arts program that uses songwriting to explore issues of incarceration, equity, justice, and community. The project will involve three study populations: a) residents at a transition home for nonviolent, nonsexual ex-offenders who have been released or diverted from incarceration; b) pre-service professionals in music education and social work enrolled as students at James Madison University; and c) community members in Harrisonburg, Virginia. As part of the arts program being studied, project staff will facilitate weekly sessions in which transitional home residents engage in self-reflection, share their stories, and are coached in generating music and/or other artworks inspired by their stories. Quantitative and qualitative data will be collected from the populations of interest. Resulting artworks will be shared with the community through live, public performance.</p>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">James Madison University</div></div></div>
<a href="/content/caregiving-research-institute">3626</a>
Caregiving Research Institute
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/caregiving-research-institute"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon26.jpg?itok=K8_u_Q45" width="100" height="49" alt="Music therapy" /></a></div></div></div>
Tamara Underiner, PhD
Tamara
Underiner
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Arizona State University will develop a new Caregiving Research Initiative within its Creative Health Collaborations research hub, which will examine the role of three different art forms in supporting three different caregiving contexts. The art forms and contexts are: 1) theater-making for parents and families of children with special needs, 2) technology-enhanced narrative expression for families of cancer patients, and 3) music for families of veterans suffering post-traumatic stress disorder. The Lab's keystone study will be conducted in partnership with Childsplay Theatre Company in Tempe, Arizona. Products likely to result from this Lab include: peer-review research journal publications, conference presentations, a best-practices guide for potential collaborators and a workbook or manual that may be used by other theater companies developing their own programming for working with families of special-needs children, and tools for the caregivers themselves.</p>
<p>The research agenda aims to address the following research questions:</p>
<ul>
<li>What are the social, emotional, physical, and/or physiological health benefits of participating in the arts for individuals, groups, or societies?</li>
<li>What physiological or psychological mechanisms or group dynamics are at work in achieving those benefits or related outcomes?</li>
<li>What kinds of art forms are invoked in these relationships, and at what levels of participation?</li>
<li>How do these benefits or related outcomes vary by one's age, socioeconomic characteristics, other demographic and behavioral patterns, and/or by health or disability status?</li>
</ul>
</div></div></div>
<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Lab</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Arizona State University</div></div></div>
<div class="field field-name-field-other-key-personnel field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><ul>
<li>David Coon, PhD</li>
<li>Elizabeth Reifsnider, PhD</li>
<li>Stephani Etheridge Woodson, PhD</li>
<li>Shelby Langer, PhD</li>
</ul>
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<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p><img alt="Arizona State University logo" height="47" src="/sites/g/files/tkssra6086/f/wysiwyg/Institution-logo/asu.png" width="169" /></p>
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<a href="/content/effects-music-based-intervention-mbi-neurodevelopment-and-pain-response-preterm-infants">3681</a>
Effects of Music Based Intervention (MBI) on Neurodevelopment and pain Response in Preterm Infants
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/effects-music-based-intervention-mbi-neurodevelopment-and-pain-response-preterm-infants"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon27.jpg?itok=7YNdueAn" width="100" height="49" alt="Effects of Music Based Intervention (MBI) on Neurodevelopment and pain Response in Preterm Infants" /></a></div></div></div>
Sonya Grace Wang, MD
Sonya
Wang
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>In 2018, the World Health Organization reported 15 million (>1 in 10) preterm births with rising annual rates. 50% of preterm infants suffer from neurodevelopmental impairments, and all preterm infants experience high volumes of painful procedures as part of medical care. Preterm music intervention shows immediate physiologic improvements in heart rate and oxygen saturation, as well as improved physiologic responses to pain. What remains unknown is how music impacts preterm brain maturation, neurodevelopment, and pain responses in preterm infants. We propose a R61 project to explore biological mechanisms of music based intervention (MBI) on preterm brain maturation and neurodevelopment using electroencephalography (EEG) and event related potentials (ERPs). EEG captures electrical potential oscillations of the brain which yields valuable information about brain function. Serial EEGs can track brain maturation in preterm infants. ERPs quantify electrical brain potentials changes time-locked with a stimulus. ERPs at 1 month corrected age test recognition memory function and cognitive processing and offers another objective measure to study the early effects of the MBI’s on neurodevelopment. The R61 will also explore the behavioral processes underlying effects of MBI on pain using EEG and the premature infant pain profile (PIPP). In preterm infants, central EEG amplitudes change when time-locked to a painful stimulus and PIPP scores scale pain responses with painful procedures. Specific recorded lullabies with simple arpeggiated accompaniment will be played for 6 weeks in a small randomized, blinded, controlled study of 50 medically stable 30 week preterms. Exploratory R61 findings will be assessed by specific Go/NoGo milestones that provide insight into the effects of MBI on biological mechanisms underlying neurodevelopment and behavioral processes underlying pain. By achieving one of the Go/NoGo milestones, the proposal progresses to the R33 proof of concept pilot clinical trial with an additional 100 randomized subjects that will assess two primary outcomes measures: 1) MBI effects on Late Neurodevelopment using Bayley’s III neurodevelopmental testing at 6 month corrected age, and 2) Cumulative effects of MBI on Pain Response using longitudinal comparisons of baseline PIPP scores and final PIPP scores after 4 weeks of MBI. Secondary measures would explore more nuanced aspects of neurodevelopment: 1) MBI effects on brain maturation with expanded analyses of EEG-sleep components; 2) repeat ERP analysis at 6 months corrected age with expanded memory and cognitive testing (additional mismatch negativity paradigms); and pain response: 3) MBI effects on pain related EEG responses with comparative analyses of central EEG amplitude changes to the frontal, parietal, temporal, and occipital lobes.</p>
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<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R61</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Minnesota</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10016175&icde=52558029&ddparam=&ddvalue=&ddsub=&cr=1&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
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<a href="/content/effects-intensive-orchestral-music-training-early-school-years-experimental-study">8486</a>
Effects of intensive, orchestral music training in the early school years: An experimental study
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/effects-intensive-orchestral-music-training-early-school-years-experimental-study"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon25_3.jpg?itok=wEG0G1kC" width="100" height="49" alt="" /></a></div></div></div>
Ellen Winner
Ellen
Winner
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a randomized, controlled study that will evaluate the effects of intensive, instrumental music training on at-risk elementary school students. Researchers will focus on the students' cognitive and affective development and their attitudes toward school. Within a longitudinal sample of the participating after-school programs, the researchers will examine differences in program quality, curriculum, classroom climate, and teacher background, in an attempt to find differences related to student outcomes such as greater executive function and self-perception.</p>
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<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Trustees of Boston College</div></div></div>
<a href="/content/musical-bridges-memory%E2%84%A2-music-intervention-persons-dementia-and-familial-caregivers">5096</a>
Musical Bridges to Memory™: A music intervention for persons with dementia and familial caregivers
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/musical-bridges-memory%E2%84%A2-music-intervention-persons-dementia-and-familial-caregivers"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon15_1.jpg?itok=GEQWjL0M" width="100" height="49" alt="Musical Bridges to Memory™: A music intervention for persons with dementia and familial caregivers" /></a></div></div></div>
Jeffrey Wolfe
Jeffrey
Wolfe
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>To support a mixed-methods, experimental study examining outcomes of a music-based program for older adults with dementia and their caregivers. Individuals with moderate-to-severe dementia living in memory care facilities and their caregivers will be placed into one of two groups: 1) Musical Bridges to Memory (MBM), a 12-week music program, or 2) a control group who receives standard care without a music program. In MBM, caregivers will engage weekly in communication skills training. Adults with dementia will listen to a set of pre-recorded music, and pairs of adults with dementia and their caregivers will attend a live music performance followed by a breakout group to practice communication skills. Assessment tools for both the intervention group and the control group will include pre- and post-measures and behavioral observations of social behaviors for adults with dementia and their caregivers. There will be separate measures for companion satisfaction among caregivers, and for mood and neuropsychiatric symptoms in adults with dementia.</p>
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<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA Research Grant</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NEA</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Institute for Therapy Through the Arts</div></div></div>
<a href="/content/effect-music-intervention-infants-brainstem-encoding-speech">3786</a>
Effect of Music Intervention on Infants' Brainstem Encoding of Speech
<div class="field field-name-field-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><a href="/content/effect-music-intervention-infants-brainstem-encoding-speech"><img typeof="foaf:Image" src="https://soundhealth.ucsf.edu/sites/g/files/tkssra6086/f/styles/thumbnail/public/FeatPro_image_icon29.jpg?itok=ZBX94knk" width="100" height="49" alt="Effect of Music Intervention on Infants' Brainstem Encoding of Speech" /></a></div></div></div>
Tian Zhao, PhD
Tian
Zhao
<div class="field field-name-field-project-summary field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Music learning that starts early in development has profound and long-lasting benefits later in life, within and beyond the music domain, in important areas such as speech and language skills, cognitive skills and social/emotional skills. Previously, work by the PI demonstrated that a short-term music intervention at as early as 9 months of age, during the ‘sensitive period’ for speech learning, can already affect cortical processing beyond music. That is, infant who underwent the music intervention also exhibited enhanced cortical processing of nonnative speech compared to the controls who underwent free play sessions. The proposed project aims to expand on these results and investigate the extent of the effects from the music intervention in infancy, more specifically, whether the music intervention can already modulate speech encoding at the lower level auditory brainstem. Understanding this question is critical from a theoretical and an application perspective. Theoretically, the results will improve the basic scientific understanding of mechanisms underlying the effects related to music intervention and its interaction with early development and speech learning. In practice, the knowledge we gain from the basic research will help future implementation of early music intervention programs as an alternative method to improve early speech and later language learning, for typically developing infants and more importantly, for infants at-risk for speech and language disorders. The first study (Aim 1) will measure infants’ brainstem encoding of nonnative lexical tones at 7 months and 11 months of age. The results from this group will serve as controls for Aim 2. At the same time, the results from Aim 1 will also establish the typical developmental trajectory for brainstem encoding of lexical tones, which has not been established before. The results will thus also expand our current understanding of behavioral and neural changes that take place during the ‘sensitive period’ for phonetic learning. In the second study (Aim 2), infants will complete the previously-established music intervention starting at 9 months of age, in addition to the brainstem measurements at 7 and 11 months of age. Their results will be compared to the controls (Aim 1) to address the effects related to the music intervention. Together, the proposed study will further our understanding of the effect related to music intervention in infancy and its underlying mechanisms. This project will also help the PI to take a big step towards her long-term goal to apply early music intervention to help infants at-risk for communication disorders.</p>
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<div class="field field-name-field-funding-source field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH R21</div></div></div>
<div class="field field-name-field-nih-type field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">NIH</div></div></div>
<div class="field field-name-field-institution field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">University of Washington</div></div></div>
<div class="field field-name-field-research-lab-webpage field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>For more information on this project, see their <a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=10016848&icde=53088972&ddparam=&ddvalue=&ddsub=&cr=1&csb=default&cs=ASC&pball=">NIH Research Portfolio</a>.</p>
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