Title | Decreasing Delirium Through Music: A Randomized Pilot Trial. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Khan SH, Xu C, Purpura R, Durrani S, Lindroth H, Wang S, Gao S, Heiderscheit A, Chlan L, Boustani M, Khan BA |
Journal | Am J Crit Care |
Volume | 29 |
Issue | 2 |
Pagination | e31-e38 |
Date Published | 2020 03 01 |
ISSN | 1937-710X |
Abstract | BACKGROUND: Management of delirium in intensive care units is challenging because effective therapies are lacking. Music is a promising nonpharmacological intervention. OBJECTIVES: To determine the feasibility and acceptability of personalized music (PM), slow-tempo music (STM), and attention control (AC) in patients receiving mechanical ventilation in an intensive care unit, and to estimate the effect of music on delirium. METHODS: A randomized controlled trial was performed in an academic medical-surgical intensive care unit. After particular inclusion and exclusion criteria were applied, patients were randomized to groups listening to PM, relaxing STM, or an audiobook (AC group). Sessions lasted 1 hour and were given twice daily for up to 7 days. Patients wore noise-canceling headphones and used mp3 players to listen to their music/audiobook. Delirium and delirium severity were assessed twice daily by using the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) and the CAM-ICU-7, respectively. RESULTS: Of the 1589 patients screened, 117 (7.4%) were eligible. Of those, 52 (44.4%) were randomized, with a recruitment rate of 5 patients per month. Adherence was higher in the groups listening to music (80% in the PM and STM groups vs 30% in the AC group; P = .01), and 80% of patients surveyed rated the music as enjoyable. The median number (interquartile range) of delirium/coma-free days by day 7 was 2 (1-6) for PM, 3 (1-6) for STM, and 2 (0-3) for AC (P = .32). Median delirium severity was 5.5 (1-7) for PM, 3.5 (0-7) for STM, and 4 (1-6.5) for AC (P = .78). CONCLUSIONS: Music delivery is acceptable to patients and is feasible in intensive care units. Further research testing use of this promising intervention to reduce delirium is warranted. |
DOI | 10.4037/ajcc2020175 |
Alternate Journal | Am. J. Crit. Care |
PubMed ID | 32114612 |
Grant List | R01 AG040220 / AG / NIA NIH HHS / United States UL1 TR001108 / TR / NCATS NIH HHS / United States R01 AG055391 / AG / NIA NIH HHS / United States R01 HL131730 / HL / NHLBI NIH HHS / United States R01 AG030618 / AG / NIA NIH HHS / United States |