Title | Randomized clinical trial of therapeutic music video intervention for resilience outcomes in adolescents/young adults undergoing hematopoietic stem cell transplant: a report from the Children's Oncology Group. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Robb SL, Burns DS, Stegenga KA, Haut PR, Monahan PO, Meza J, Stump TE, Cherven BO, Docherty SL, Hendricks-Ferguson VL, Kintner EK, Haight AE, Wall DA, Haase JE |
Journal | Cancer |
Volume | 120 |
Issue | 6 |
Pagination | 909-17 |
Date Published | 2014 Mar 15 |
ISSN | 1097-0142 |
Keywords | Adaptation, Psychological, Adolescent, Adult, Anxiety, Child, Family Relations, Female, Hematopoietic Stem Cell Transplantation, Hematopoietic Stem Cells, Hope, Humans, Male, Music Therapy, Resilience, Psychological, Social Isolation, Social Support, Stress, Psychological, Young Adult |
Abstract | BACKGROUND: To reduce the risk of adjustment problems associated with hematopoietic stem cell transplant (HSCT) for adolescents/young adults (AYAs), we examined efficacy of a therapeutic music video (TMV) intervention delivered during the acute phase of HSCT to: 1) increase protective factors of spiritual perspective, social integration, family environment, courageous coping, and hope-derived meaning; 2) decrease risk factors of illness-related distress and defensive coping; and 3) increase outcomes of self-transcendence and resilience. METHODS: This was a multisite randomized, controlled trial (COG-ANUR0631) conducted at 8 Children's Oncology Group sites involving 113 AYAs aged 11-24 years undergoing myeloablative HSCT. Participants, randomized to the TMV or low-dose control (audiobooks) group, completed 6 sessions over 3 weeks with a board-certified music therapist. Variables were based on Haase's Resilience in Illness Model (RIM). Participants completed measures related to latent variables of illness-related distress, social integration, spiritual perspective, family environment, coping, hope-derived meaning, and resilience at baseline (T1), postintervention (T2), and 100 days posttransplant (T3). RESULTS: At T2, the TMV group reported significantly better courageous coping (Effect Size [ES], 0.505; P = .030). At T3, the TMV group reported significantly better social integration (ES, 0.543; P = .028) and family environment (ES, 0.663; P = .008), as well as moderate nonsignificant effect sizes for spiritual perspective (ES, 0.450; P = .071) and self-transcendence (ES, 0.424; P = .088). CONCLUSIONS: The TMV intervention improves positive health outcomes of courageous coping, social integration, and family environment during a high-risk cancer treatment. We recommend the TMV be examined in a broader population of AYAs with high-risk cancers. |
DOI | 10.1002/cncr.28355 |
Alternate Journal | Cancer |
PubMed ID | 24469862 |
PubMed Central ID | PMC3947727 |
Grant List | R01NR008583 / NR / NINR NIH HHS / United States R01 CA162181 / CA / NCI NIH HHS / United States U10CA098543 / CA / NCI NIH HHS / United States U10 CA095861 / CA / NCI NIH HHS / United States P30 CA082709 / CA / NCI NIH HHS / United States UL1 TR001108 / TR / NCATS NIH HHS / United States U10CA095861 / CA / NCI NIH HHS / United States T32 NR007066 / NR / NINR NIH HHS / United States U10 CA098543 / CA / NCI NIH HHS / United States U10 CA180886 / CA / NCI NIH HHS / United States R01 NR008583 / NR / NINR NIH HHS / United States |